Assessing safety at work using an adaptive neuro-fuzzy inference system (ANFIS) approach aided by partial least squares structural equation modeling (PLS-SEM)
Publication date: March 2020Source: International Journal of Industrial Ergonomics, Volume 76Author(s): Erman Çakıt, Andrzej Jan Olak, Waldemar Karwowski, Tadeusz Marek, Irena Hejduk, Redha TaiarAbstractThe main objective of this research was to apply an adaptive neuro-fuzzy inference system (ANFIS) approach aided by Partial Least Squares Structural Equation Modeling (PLS-SEM) to assess safety at work, defined as employee propensity to follow safety regulations, including safe work practices at the workplace. A survey with seven main components: 1) use of mobile technology, 2) tacit safety knowledge, 3) explicit safety knowledge, 4) attitudes toward safety: psychological aspects, 5) attitudes toward safety: emotional aspects, 6) safety culture: behavioral aspects, and 7) safety culture: psychological aspects, was used for this purpose. Workers from three manufacturing companies located in southeastern Poland completed a paper-based survey. PLS-SEM, combined with an adaptive neuro-fuzzy inference system (ANFIS) method, was used to develop the study model and determine its main components. The results showed that tacit safety knowledge, attitudes toward safety: psychological aspects, attitudes toward safety: emotional aspects, safety culture: behavioral aspects, safety culture: psychological aspects, and the use of mobile technology were significant factors influencing the perceived safety at work. Moreover, the results of the ANFIS modeling approach showed that behavio...
AbstractBackgroundPrevious studies have identified that patients withEGFR mutations tend to have better responses to targeted therapy, as well as chemotherapy; however, the effect of genetic alterations in terms of radiotherapy (RT) ‐related outcomes has not been fully assessed. We studied the impact of common non‐small cell lung cancer (NSCLC) genetic alterations (EGFR,ALK andKRAS) in relation to objective response rate (ORR) to RT in patients with brain metastases.MethodsFrom 2009 –2015, 153 patients with an available genotyping status were treated with whole‐brain irradiation (WBI) before receiving systemic ...
ConclusionsEndostar delivered by CIV with CCRT may be a better option than IV in terms of potential survival and safety for unresectable stage III NSCLC.Key pointsSignificant findings of the study Endostar delivered by continuous intravenous pumping might achieve more favorable survival over intravenous injection and reduce adverse hematological reactions in patients with unresectable stage III NSCLC treated with Endostar combined with CCRT.What this study adds The administration route of recombinant human endostatin is also one key factor for survival and safety to consider when treating patients with unresectable stage III NSCLC.
ConclusionsThe use of osimertinib immediately after nivolumab significantly increased the frequency of grade 3 or higher hepatotoxicity in patients with advanced NSCLC harboringEGFR mutation acquired T790M resistance.
Authors: Dietrich DE, Bode L, Spannhuth CW, Hecker H, Ludwig H, Emrich HM Abstract BACKGROUND: Whether Borna disease virus (BDV-1) is a human pathogen remained controversial until recent encephalitis cases showed BDV-1 infection could even be deadly. This called to mind previous evidence for an infectious contribution of BDV-1 to mental disorders. Pilot open trials suggested that BDV-1 infected depressed patients benefitted from antiviral therapy with a licensed drug (amantadine) which also tested sensitive in vitro. Here, we designed a double-blind placebo-controlled randomized clinical trial (RCT) which cross-lin...
Date: Friday, 02 28, 2020; Speaker: Jonathan Wasserman, Staff Physician, SickKids; BG 10-CRC; FAES 1&2
Date: Tuesday, 03 03, 2020; Speaker: TBD, TBD; Dr. Jeremy Veenstra-VanderWeele, Columbia University; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
Date: Tuesday, 03 10, 2020; Speaker: TBD, TBD; Dr. Jeff Elias, University of Virginia School of Medicine; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
Date: Tuesday, 03 10, 2020; Speaker: Staff NIH Library; Building: Building 10 (Clinical Center); NIH Library Training Room
Date: Wednesday, 03 11, 2020; Speaker: Staff NIH Library; Building: Building 10 (Clinical Center); This class is presented as a webinar only; Videocast Event
Date: Thursday, 03 12, 2020; Speaker: BTRIS instructor; Building: Building 10 (Clinical Center); NIH Library Training Room