Disparities Seen in Outcomes for Young Adults With CRC
TUESDAY, Jan. 28, 2020 -- Worse outcomes are seen for young adult (YA) patients with colorectal cancer (CRC) living in the lowest income and education areas, according to a study presented at the American Society of Clinical Oncology annual...
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ConclusionThe increase of early-onset CRC incidence suggests more prevention initiatives are urgently warranted for young adults in the near future. Targeted and effective prevention measures are still needed among elderly populations.
(Wiley) A population-based analysis from England indicates that the incidence of colorectal cancer is increasing rapidly in young adults. The findings, which are published in BJS (British Journal of Surgery), suggest that colorectal cancer should no longer be considered a disease of older people.
CONCLUSION: Colorectal cancer should no longer be considered a disease of older people. Changes in incidence rates should be used to inform future screening policy, preventative strategies and research agendas, as well as increasing public understanding that younger people need to be aware of the symptoms of colorectal cancer. PMID: 32149386 [PubMed - as supplied by publisher]
Authors: Chandrapalan S, Arasaradnam RP Abstract Introduction: The increasing incidence of colorectal cancer (CRC) in young adults warrants early and preferably non-invasive diagnostic modalities. Although the current stool-based assays have had good performance indicators for CRC detection, the overall poor uptake remains a challenging issue. However, alternative blood and urine markers are emerging.Areas covered: This paper discusses the various urinary biomarkers available for the detection of CRC. The more commonly encountered drawbacks are the small number of studies and size of the study population. We discus...
Colon and rectal cancer cases are on the rise in young adults, according to a new report from the American Cancer Society.
(American Cancer Society) The burden of colorectal cancer is swiftly shifting to younger individuals as incidence increases in young adults and declines in older age groups, according to the latest edition of Colorectal Cancer Statistics 2020, a publication of the American Cancer Society. A sign of the shift: the median age of diagnosis has dropped from age 72 in the late 1980s to 66 during 2015-2016; in other words, half of all new diagnoses are now in people 66 or younger.
(American College of Surgeons) Colon cancer is more likely to be lethal in children and young adults than middle-aged adults.
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In conclusion, the concept of an epigenetic clock is compelling, but caution should be taken in interpreting associations with age acceleration. Association tests of age acceleration should include age as a covariate. A Discussion of Recent Work on Allotopic Expression of Mitochondrial Genes at the SENS Research Foundation https://www.fightaging.org/archives/2020/02/a-discussion-of-recent-work-on-allotopic-expression-of-mitochondrial-genes-at-the-sens-research-foundation/ A paper published last month outlines recent progress on allotopic expression of mitochondrial genes carried out by the SENS Research ...