Skin cream used to treat GENITAL WARTS could protect people against diseases carried by mosquitoes

Scientists studied the effect of the cream, which is sold as Imiquimod or Aldara, on four types of virus transmitted by mosquitoes, including Zika and Chikungunya.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

Related Links:

Authors: Ma B, Yuan J, Chen S, Huang K, Wang Q, Ma J, Lin R, Zhang L, Zhou Y, Wang T, Walton SF, Pan X, Chen G, Wang Y, Ni G, Liu X Abstract Genital warts, which are one of the most common sexually transmitted diseases (STDs), result from persistent infection with human papillomavirus (HPV), especially subtypes 6 or 11. Topical application of 5% imiquimod cream is currently recommended as a first-line treatment choice for genital warts, but the clearance and patient compliance rates remain less than sufficient. In the current study, we developed a temperature-sensitive gel that contains the host-defense peptides ca...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Authors: Bonfim CMD, Monteleoni LF, Calmon MF, Cândido NM, Provazzi PJS, Lino VS, Rabachini T, Sichero L, Villa LL, Quintana SM, Melli PPDS, Primo FL, Amantino CF, Tedesco AC, Boccardo E, Rahal P Abstract Vulvar intraepithelial neoplasia (VIN) is associated with human papillomavirus (HPV) infection. Curcumin is a natural bioactive compound with antineoplastic properties. The use of nanoparticles containing curcumin could allow a better performance of this compound in therapies. So, VIN biopsies were collected and HPV DNA detection was performed by PCR, positive samples were genotyped by Restriction Fragment L...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
(Bar-Ilan University) The time it currently takes to diagnose coronavirus poses one of the greatest challenges in treating infected patients and increases the risk of exposure. Using a new technology developed by Dr. Amos Danielli, of Bar-Ilan University, saliva tests can be analyzed within 15 minutes. The technology has already been proven to reduce the diagnostic time of Zika virus and is currently being used in the Israel Ministry of Health's central virology laboratory.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
ebi R, Costa ACD Abstract Aedes aegypti is associated with epidemic diseases in Brazil, such as urban yellow fever, dengue, and more recently, chikungunya and Zika viruses infections. More information about Ae. aegypti infestation is fundamental to virological surveillance in order to ensure the effectiveness of control measures in use. Thus, the present study aims to identify and compare infestation and infectivity of Ae. aegypti females in Macapa city, Amapa State (Amazon region), Brazil, between the epidemiological weeks 2017/02 and 2018/20. A total number of 303 Ae. aegypti females were collected at 21 fixed c...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
Future Virology, Ahead of Print.
Source: Future Virology - Category: Virology Authors: Source Type: research
ConclusionColorectal squamous cell carcinoma is a rare disease. In cases of colorectal squamous cell carcinoma, metastatic disease at any other location has to be excluded. Human papillomavirus genotyping is essential in this context. Discussion of the treatment strategies should be interdisciplinary and include chemoradiation therapy and radical surgery.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Conclusions/SignificanceBoth SISA and SISAL were able to predict arbovirus hospitalization with a high degree of accuracy in our dataset. These algorithms will need to be tested and validated on new data from future patients. Machine learning is a powerful prediction tool and provides an excellent option for new management tools and clinical assessment of arboviral infection.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
During pregnancy, the organization of complex tolerance mechanisms occurs to assure non-rejection of the semiallogeneic fetus. Pregnancy is a period of vulnerability to some viral infections, mainly during the first and second trimesters, that may cause congenital damage to the fetus. Recently, Zika virus (ZIKV) infection has gained great notoriety due to the occurrence of congenital ZIKV syndrome, characterized by fetal microcephaly, which results from the ability of ZIKV to infect placental cells and neural precursors in the fetus. Importantly, in addition to the congenital effects, studies have shown that perinatal ZIKV...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Squamous cell carcinoma of the head and neck (SCCHN) is the seventh most common malignancy and is responsible for 3.7% of cancer deaths worldwide [1]. The main risk factors are alcohol and tobacco. The human papillomavirus (HPV) is another risk factor for oropharyngeal cancer (OPC) and its incidence is rising [2].The 5-year survival rate of SCCHN is still poor, ranging from 25% - 60% depending on tumor staging and site [3]. Most patients present with locally-advanced disease, but despite multimodal treatment including chemoradiation or surgery followed by (chemo)radiation, more than 50% of patients will relapse.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Hot Topic Source Type: research
During host–virus co-evolution, cells develop innate immune systems to inhibit virus invasion, while viruses employ strategies to suppress immune responses and maintain infection. Here, we reveal that Zika virus (ZIKV), a re-emerging arbovirus causing public concerns and devastating complications, restricts host immune responses through a distinct mechanism. ZIKV nonstructural protein 5 (NS5) interacts with the host retinoic acid-inducible gene I (RIG-I), an essential signaling molecule for defending pathogen infections. NS5 subsequently represses K63-linked polyubiquitination of RIG-I, attenuates the phosphorylation...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
More News: Chikungunya | Genital Warts | Health | Skin | Warts | Zika Virus