123I-Iomazenil Single Photon Emission Computed Tomography Visualizes Recovery of Neuronal Integrity by Bone Marrow Stromal Cell Therapy in Rat Infarct Brain [Basic Sciences]

Conclusions— The present findings strongly suggest that the BMSCs may enhance functional recovery by improving the neuronal integrity in the peri-infarct area, when directly transplanted into the infarct brain at clinically relevant timing. 123I-IMZ single photon emission computed tomography may be a promising modality to scientifically prove the beneficial effects of BMSC transplantation on the host brain in clinical situation.

http://stroke.ahajournals.org/cgi/content/short/44/10/2869?rss=1

Source: Stroke - September 23, 2013 Category: Neurology Authors: Saito, H., Magota, K., Zhao, S., Kubo, N., Kuge, Y., Shichinohe, H., Houkin, K., Tamaki, N., Kuroda, S. Tags: Animal models of human disease, Acute Cerebral Infarction, PET and SPECT, Other Stroke Treatment - Medical, Other Stroke Treatment - Surgical Basic Sciences Source Type: research