Demethylation of Di-Methylation of Lysine 4 on Histone 3 Is Inhibited by General Control Nondepressible 5-Induced Acetylation of Lysine-Specific Demethylase 1.

CONCLUSIONS: GCN5-induced acetylation of LSD1 impeded progression of colon cancer by inhibiting the demethylation of histone.
PMID: 31982102 [PubMed - as supplied by publisher]

Source: The American Journal of the Medical Sciences - January 6, 2020 Category: General Medicine Authors: Jiao M, Xia L, Chen J, Cui Z Tags: Am J Med Sci Source Type: research