Heart attack: Noticing this warning sign in your ear shouldn’t be ignored

A HEART ATTACK is when the blood supply that normally nourishes the heart with oxygen is cut off and the heart muscle begins to die. Knowing the early warning signs of a heart could save a life and spotting this unusual sign in the ear could mean you're at risk.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Authors: Song Z, Gao R, Yan B Abstract Cardiovascular disease is still the main cause of morbidity and mortality worldwide. Currently, the frontier of research into cardiovascular disease is the field of non-coding RNA. In this review, information was collected on the use of micro-RNAs as non-invasive biomarkers and their role in pathophysiological processes and therapeutic applications. In the case of microRNA-1 and microRNA-133, the roles and regulatory mechanisms of them are reviewed for arrhythmia, myocardial infarction, diabetic cardiomyopathy, myocardial hypertrophy, cardiomyocyte differentiation, and cell re...
Source: Reviews in Cardiovascular Medicine - Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research
Authors: Liu Y, Zeng Z, Yu X, Li T, Yao Y, Chen R, Zheng J Abstract The purpose of this study is to investigate the effect of lipoprotein(a) level on long-range prognosis after Percutaneous Coronary Intervention (PCI) in patients with low-density lipoprotein cholesterol (LDL-C) goal attainment. In this retrospective study, 350 patients in Coronary artery disease (CAD) with LDL-C less than 1.8 mmol/L were enrolled in the Guangdong Institute of Cardiovascular Diseases from January 2011 to December 2013. Follow-up was 1 year after PCI. According to the median value of the study population based on Lp(a), the patients ...
Source: Reviews in Cardiovascular Medicine - Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research
Authors: Chen E, Cai W, Hu D, Chen L Abstract Remote ischemic conditioning is usually associated with cardioprotective intervention against ischemia-reperfusion. However, the effect of remote ischemic preconditioning (RIC-pre) completed before myocardial reperfusion with intermittent limb ischemia-reperfusion in patients with STEMI undergoing primary percutaneous coronary intervention (PPCI) is unclear. PubMed, EMBASE, and the Cochrane Library were fully searched from the beginning of each database up to September 2019 to find seven RCTs, a total of 2796 patients with STEMI undergoing PPCI with RIC-pre and 2818 pat...
Source: Reviews in Cardiovascular Medicine - Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research
This study aimed to ascertain whether tiotropium/olodaterol (T/O) 5/5 μg fixed-dose combination (FDC) may modulate the risk of main cardiovascular outcomes in COPD patients enrolled in randomized controlled trials (RCTs). A meta-analysis (CRD42017070100) was performed by selecting RCTs reporting raw data from the ClinicalTrials.gov database concerning the impact of T/O 5/5 µg FDC vs. monocomponents on the occurrence of specific cardiovascular serious adverse events: arrhythmia, heart failure, myocardial infarction, and stroke. Data were reported as relative risk and 95% Confidence Interval, and the r...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research
Conclusion: Cerebral aneurysm coiling could be considered as the first choice of treatment in the case of acute MI with hemodynamic stability, before carrying out cardiac endovascular intervention or antiplatelet medication to reduce the risk of rebleeding from a brain aneurysm. PMID: 32257575 [PubMed - as supplied by publisher]
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research
We carefully read with interest the recent article by Zhao et al. [1] concerning “Circulating Serpina3 levels predict the major adverse cardiac events in patients with myocardial infarction”. This suggests that serine proteinase inhibitor A3 (Serpina3), also called alpha-1antichymotrypsin, may be a powerful prognostic biomarker for major adverse cardiovascular events in pati ents with acute myocardial infarction (MI). Although the exact mechanism is still unclear, this finding means that inhibition of Serpina3 may act as a potential therapeutic strategy for myocardial ischemia/reperfusion (I/R) injury heart.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Letter to the Editor Source Type: research
The management of stable ischaemic heart disease continues to evolve with the recently presented ISCHEMIA trial demonstrating that revascularisation therapy (primarily percutaneous coronary intervention, PCI) does not reduce the risk of major adverse cardiac events in high risk stable angina patients with moderate-severe ischaemia [1]. Indeed, the ISCHEMIA trial reported more acute myocardial infarction (AMI) in the first 6  months after randomisation amongst those managed with PCI therapy as compared to those treated with optimal medical therapy alone.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
CONCLUSIONS: In patients with STEMI and MVD, FFR-guided complete revascularization is more beneficial in terms of outcome and health-care costs compared to IRA-only revascularization at 36 months. PMID: 32250250 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
CONCLUSIONS: Despite the high level of complexity of the studied population, RA turned out to be an effective procedure with a low rate of in-hospital complications and demonstrated good immediate and mid-term results. PMID: 32250249 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Source: Journal of Biomedical Nanotechnology - Category: Nanotechnology Authors: Tags: Articles Source Type: research
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