Generalized acanthosis nigricans without systemic disease associated.

Generalized acanthosis nigricans without systemic disease associated.
Dermatol Online J. 2013;19(9):19614
Authors: Denadai R, Souto RM, Auada-Souto MP
Abstract
Acanthosis nigricans (OMIM ID % 100600) is a dermatosis characterized by velvety hyperpigmentation, skin thickening, and papillomatosis. It mainly affects flexural areas. In most cases, the generalized form is related to malignancy in adults; it is rarely reported in the absence of systemic disease in children and adolescents. The present report is aimed at describing an unusual case of generalized acanthosis nigricans in a 17 year-old patient, in which, after extensive investigation (clinical, laboratorial and by imaging methods) no association with systemic disease was found.
PMID: 24050288 [PubMed - in process]

Source: Dermatol Online J - September 26, 2013 Category: Dermatology Authors: Denadai R, Souto RM, Auada-Souto MP Tags: Dermatol Online J Source Type: research