Multimorbidity in COPD, does sleep matter?

Multimorbidity in COPD, does sleep matter? Eur J Intern Med. 2020 Jan 21;: Authors: Vanfleteren LE, Beghe B, Andersson A, Hansson D, Fabbri LM, Grote L Abstract A good night's sleep is a prerequisite for sustainable mental and physical health. Sleep disorders, including sleep disordered breathing, insomnia and sleep related motor dysfunction (e.g., restless legs syndrome), are common in patients with chronic obstructive pulmonary disease (COPD), especially in more severe disease. COPD is commonly associated with multimorbidity, and sleep disorders as a component of this multimorbidity spectrum have a further negative impact on COPD-related comorbidities. Indeed, concomitant diseases in COPD and in obstructive sleep apnea (OSA) are similar, suggesting that the combination of COPD and OSA, the so called OSA-COPD overlap syndrome (OVS), affects patient outcomes. Potential clinically important interactions of OVS exist in cardiovascular and metabolic disease, arthritis, anxiety, depression, neurocognitive disorder and the fatigue syndrome. Correct diagnosis for recognition and treatment of sleep-related disorders in COPD is recommended. However, surprisingly limited information is available and further research and improved diagnostic tools are needed. In the absence of clear evidence, we agree with the recommendation of the Global Initiative on Chronic Obstructive Lung Disease that sleep disorders should be actively searched for and treated in patients with...
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Eur J Intern Med Source Type: research

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Authors: Finley JR, Wixted JT, Roediger HL Abstract Recent research in the eyewitness identification literature has investigated whether simultaneous or sequential lineups yield better discriminability. In standard eyewitness identification experiments, subjects view a mock-crime video and then are tested only once, requiring large samples for adequate power. However, there is no reason why theories of simultaneous versus sequential lineup performance cannot be tested using more traditional recognition memory tasks. In two experiments, subjects studied DRM (Deese-Roediger-McDermott) word lists (e.g., bed, rest, tir...
Source: Memory and Cognition - Category: Neuroscience Tags: Mem Cognit Source Type: research
Contributors : Alexander B Niculescu ; Helen Le-NiculescuSeries Type : Expression profiling by arrayOrganism : Homo sapiensShort-memory dysfunction is a key early feature of Alzheimer Disease. Psychiatric patients may be at higher risk for memory dysfunction and subsequent Alzheimer due to the negative effects of stress and depression on the brain. We carried out longitudinal within-subject studies in male and female psychiatric patients to identify blood gene expression biomarkers that track short term memory as measured by the retention measure in the Hopkins Verbal Learning Test. These biomarkers were prioritized with a...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
Background. Frailty is a clinically recognized syndrome of decreased physiological reserve and a key contributor to suboptimal clinical outcomes in various lung disease groups. Interstitial lung disease (ILD) is fast approaching chronic obstructive pulmonary disease as the number one indication for lung transplantation worldwide. Our aim was to assess whether frailty is a predictor of mortality in patients with ILD referred for lung transplantation in an Australian cohort. Methods. Consecutive patients with ILD referred or on the waiting list for lung transplantation from May 2013 to December 2017 underwent frailty as...
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research
Conclusion: The current review identified strong, high-quality evidence to recommend hip muscle strengthening in the conservative management of persons with knee OA. Further research is needed to establish the underlying mechanisms for the clinical benefits.
Source: Journal of Geriatric Physical Therapy - Category: Physiotherapy Tags: Systematic Reviews Source Type: research
Publication date: Available online 31 March 2020Source: Life SciencesAuthor(s): Mohsen Enayati, Belal Mosaferi, Judith R. Homberg, Danielle Mendes Diniz, Ali-Akbar Salari
Source: Life Sciences - Category: Biology Source Type: research
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Hi everyone, I just made this account but I've been active on this forum for over 8 years. I withdrew from med during 3rd semester due to anxiety (W's for that semester but ~B average for med school overall). While in med school I saw friends fail things like Step 1, Step 2 CS, or not match and have to SOAP. In med school I had trouble sleeping occasionally. Then during my 3rd semester the trouble sleeping became severe anxiety as I kept having unwanted thoughts of not matching. I think... Help a med school dropout
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Clinicians [ RN / NP / PA ] Source Type: forums
Arthritis&Rheumatology, Volume 72, Issue 4, April 2020.
Source: Arthritis and Rheumatology - Category: Rheumatology Tags: ACR Announcements Source Type: research
Arthritis&Rheumatology, Volume 72, Issue 4, April 2020.
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Arthritis&Rheumatology, Volume 72, Issue 4, April 2020.
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