Comparison of symptomatic and functional responses to vagus nerve stimulation in ANTHEM ‐HF, INOVATE‐HF, and NECTAR‐HF

ConclusionsIn this post ‐hoc analysis, differences in patient demographics were seen and may have caused the differential responses in symptoms and function observed in association with VNS. Major differences in technology platforms, neural targets, VNS delivery, and HR and HR variability responses could have also potent ially played a very important role. Further study is underway in a randomized controlled trial with these considerations in mind.

Source: ESC Heart Failure - January 26, 2020 Category: Cardiology Authors: Inder S. Anand, Marvin A. Konstam, Helmut U. Klein, Douglas L. Mann, Jeffrey L. Ardell, Douglas D. Gregory, Joseph M. Massaro, Imad Libbus, Lorenzo A. DiCarlo, John James E. Udelson, Javed Butler, John D. Parker, John R. Teerlink Tags: Original Research Article Source Type: research