Low molecular weight heparin (nadroparin) improves placental permeability in rats with gestational diabetes mellitus via reduction of tight junction factors.

In conclusion, GDM was associated with increased placental permeability and this may be linked with changes in TJs. LMWH intervention mediated protection against this GDM‑associated shift in placental permeability via the RAGE/NF‑κB pathway. PMID: 31974593 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31974593?dopt=Abstract

Source: Molecular Medicine Reports - January 26, 2020 Category: Molecular Biology Tags: Mol Med Rep Source Type: research