Evidence for a physiological role of pulmonary arterial baroreceptors in sympathetic neural activation in healthy humans.

In conclusion, unloading of pulmonary arterial baroreceptors reduced basal sympathetic outflow to the skeletal muscle vasculature and reset vascular-sympathetic baroreflex control of MSNA downward and leftward in healthy humans at high-altitude. These data suggest the existence of a lesser-known reflex input involved in sympathetic activation in humans. This article is protected by copyright. All rights reserved.
PMID: 31977069 [PubMed - as supplied by publisher]

Source: The Journal of Physiology - January 23, 2020 Category: Physiology Authors: Simpson LL, Meah VL, Steele A, Thapamagar S, Gasho C, Anholm JD, Drane AL, Dawkins TG, Busch SA, Oliver SJ, Lawley JS, Tymko MM, Ainslie PN, Steinback CD, Stembridge M, Moore JP Tags: J Physiol Source Type: research