Practice review: Evidence-based and effective management of pain in patients with advanced cancer.
CONCLUSION: Interventions commonly recommended by guidelines are not always supported by a robust evidence base. Research is required to evaluate the efficacy of non-steroidal anti-inflammatory drugs, anti-convulsants, anti-depressants, corticosteroids, some invasive anaesthetic techniques, complementary therapies and transcutaneous electrical nerve stimulation. PMID: 31980005 [PubMed - as supplied by publisher]
Conclusions: Most participating women considered anal cancer screening necessary and very acceptable. Longer screening intervals and adequate pain management could further increase the acceptability of repeated screening. PMID: 32218656 [PubMed - as supplied by publisher]
Conclusion: Addition of intercostal block to epidural analgesia does not confer any benefit in terms of post-operative pain, fentanyl requirements or volume achieved on spirometry.
A 60-year-old man presented to the emergency department with pain and swelling of the left lower limb, which deteriorated rapidly in 1 day. On physical examination, his left lower limb was cold, violaceous, swollen, and tender (Figure 1). In addition, no pulse was palpable in his left dorsalis pedis. He did not have a history of cancer, immobilization, recent surgery, trauma, or coagulation dysfunction. Contrast-enhanced compute d tomography revealed a venous thrombus extending from the left common iliac vein to the popliteal vein.
Pomalidomide is potentially a less painful alternative to options such as freezing and laser ablation, and it may have a lower rate of recurrence, but copays cost about $5000 for a month's supply.Medscape Medical News
Having trouble viewing this email? View it as a Web page. NIDCR's Spring 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News NIDCR News CDC’s COVID-19 Guidance for Dental Settings Dental health care personnel can find COVID-19-related information on the CDC’s Division of Oral Health website, which offers guidance and resources for clinics and health care facilities and recommen...
Opioids are the recommended form of analgesia for patients with persistent cancer pain, and regular dosing “by the clock” is advocated in many international guidelines on cancer pain management. The development of sustained-release opioid preparations has made regular dosing easier for patients. However, patients report that the intensity and impact of their cancer pain varies considerably day to day, and many try to find a trade-off between acceptable pain control and impact of cognitive (and other) adverse effects on daily activities. In acute care settings, (eg, postoperative) as-needed dosing and other opio...
The ability to sense visceral pain during appendicitis is diminished with age leading to delay in seeking health care and poorer clinical outcomes. To understand the mechanistic basis of this phenomenon, we examined visceral nociception in aged mouse and human tissue. Inflamed and noninflamed appendixes were collected from consenting patients undergoing surgery for the treatment of appendicitis or bowel cancer. Supernatants were generated by incubating samples in buffer and used to stimulate multiunit activity in intestinal preparations, or single-unit activity from teased fibres in colonic preparations, of young and old m...
No abstract available
To estimate pain reporting among residents with cancer in relation to metropolitan area segregation and NH racial and ethnic composition.