Temporal and region-specific effects of sleep fragmentation on gut microbiota and intestinal morphology in Sprague Dawley rats

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Source: Gut Microbes - Category: Microbiology Authors: Source Type: research

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Introduction: Fibromyalgia (FM) is a chronic condition of unknown aetiology, characterized by muscular pain, sleep disorders as well as gastrointestinal symptoms. Among the non-pharmacological treatments, growing evidence suggests a link between nutrition and FM.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research
Traumatic brain injury (TBI) is a leading cause of disability in the United States. With decreasing mortality rates, a higher number of patients are impacted by long-term neuropsychiatric sequelae, such as cognitive deficits, depression, anxiety, and sleep-wake disorders. These sequelae are primarily driven by the disruption of key neurotransmitter homeostasis including dopamine, norepinephrine, serotonin, and acetylcholine. Neurostimulants are centrally acting medications used to assist in restoring these neurotransmitter abnormalities and are pharmacologic options to ameliorate symptoms in post-TBI patients. Examples of ...
Source: Critical Care Nursing Quarterly - Category: Nursing Tags: Original Articles Source Type: research
Sleep plays an important role in the recovery of critically ill patients. However, patients in the intensive care unit (ICU) often suffer sleep disturbances and abnormal circadian rhythms, which may increase delirium and lengthen ICU stay. Nonpharmacologic strategies for preventing and treating sleep disturbances and delirium, such as overnight eye masks and ear plugs, are usually employed first, given the lack of adverse effects. However, a multimodal approach to care including pharmacotherapy may be necessary. Despite the limited available data supporting their use, medications such as melatonin, ramelteon, suvorexant, a...
Source: Critical Care Nursing Quarterly - Category: Nursing Tags: Original Articles Source Type: research
Publication date: Available online 21 February 2020Source: NeuroscienceAuthor(s): Diana C. Rotaru, Edwin J. Mientjes, Ype ElgersmaAbstractThe UBE3A gene is part of the chromosome 15q11-q13 region that is frequently deleted or duplicated, leading to several neurodevelopmental disorders. Angelman syndrome (AS) is caused by the absence of functional maternally derived UBE3A protein, while the paternal UBE3A gene is present but silenced specifically in neurons. Patients with AS present with severe neurodevelopmental delay, with pronounced motor deficits, absence of speech, intellectual disability, epilepsy, and sleep problems....
Source: Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 20 February 2020Source: The Annals of Thoracic SurgeryAuthor(s): Bhargavi Gali, Amy E. Glasgow, Kevin L. Greason, Rebecca L. Johnson, Robert C. Albright, Elizabeth B. HabermannAbstractBackgroundObstructive sleep apnea (OSA) is associated with increased risk of postoperative complications in non-cardiac surgery, with limited literature on cardiac surgical patients. We compared perioperative outcomes of patients with OSA to those without OSA undergoing cardiac surgery.MethodsThis was a retrospective single center cohort study of adult patients who underwent cardiac surgery from January 2010...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Mount Laurel, NJ  – February 17, 2020 – Owandy Radiology Inc., a global leader in the manufacture of dental radiology hardware and imaging software, will be introducing its new 5-year warranty program during the Chicago Midwinter Meeting in booth #4821.According to Owandy company spokesman Boris Loyez, “We’ve extended our standard 2-year warranty to 5 years with no additional upcharge to provide our customers with additional value and peace of mind. Our 5-year warranty includes our entire product line, including the I-Max 3D Cone Beam Unit, which is now our best seller since its recent upgrade ...
Source: Dental Technology Blog - Category: Dentistry Source Type: news
ConclusionCaffeine is an effective countermeasure to driver sleepiness, however, high caffeine consumers do not exhibit any benefit to driving safety indicators. In fact, there is some evidence for safety concern because high caffeine consumers self-report more crashes and worse driving safety indicators than low caffeine consumers. High caffeine consumption was associated with poor health behaviours. Further research is needed to fully understand the implications of high caffeine use. Interventions aiming to reduce truck driver sleepiness should be cautious in promotion of caffeine in isolation; a wholistic approach to im...
Source: Safety Science - Category: Occupational Health Source Type: research
Publication date: Available online 20 February 2020Source: Journal of Science and Medicine in SportAuthor(s): Jade McNeill, Steven J. Howard, Stewart A. Vella, Dylan P. CliffAbstractObjectiveTo examine whether meeting the Australian 24-Hour Movement Guidelines was associated with cognitive and psychosocial development in preschoolers.DesignProspective observational studyMethodsCross-sectional (n = 247) and 12-month longitudinal (n = 185) data from the PATH-ABC study were examined. Physical activity was assessed by accelerometry. Parents reported children’s screen time and sleep. Children w...
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Source Type: research
ConclusionsFitness tracker sleep efficiency and wake counts demonstrate clinical utility as predictive of asthma-specific night-time wakening and daily FEV1. Fitness tracker sleep data demonstrated predictive capability for daily asthma outcomes.
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
CONCLUSION: MS is beneficial where the main aim is to attain a significant and long-lasting weight loss results. The RCTs have depicted the superiority which surgical mechanisms hold over medically based therapy, for enhancing glycaemic control, and achieving remission of diabetes. This type of surgery improves life quality, reduces incidences of other obesity and diabetes relating diseases like microvascular illness, sleep apnea, fatal disorder, and fatty liver disease. PMID: 32077829 [PubMed - as supplied by publisher]
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
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