Interpersonal relationship challenges among stroke survivors and family caregivers
ConclusionsThe present study demonstrates that IPEE treatments can enhance cerebral ischemic tolerance by regulating the toll-like receptor 4 (TLR4) signaling pathway. The mechanisms of this response come in two primary forms: inhibiting MyD88 dependent pro-inflammatory pathways and activating TRIF dependent anti-inflammatory pathways.Graphical abstract
Publication date: Available online 19 February 2020Source: Canadian Journal of CardiologyAuthor(s): Hsin-Fu Lee, Yi-Hsin Chan, Pei-Ru Li, Jia-Rou Liu, Tze-Fan Chao, Lung-Sheng Wu, Shang-Hung Chang, Yung-Hsin Yeh, Chi-Tai Kuo, Lai-Chu See, Gregory Y.H. LipAbstractBackgroundEvidences of clinical outcomes for oral anticoagulants and antiplatelet treatment (APT) in atrial fibrillation (AF) patients with critical limb ischemia (CLI) are very limited.MethodsIn this nationwide retrospective cohort study collected from Taiwan National Health Insurance Research Database, 1,223 AF patients with CLI taking DOACs, warfarin, or APT wer...
ConclusionIn the presented report, in patients with nonvalvular atrial fibrillation the LAmbre offered similar long ‐term efficacy and safety in comparison to Amplatzer devices.This article is protected by copyright. All rights reserved.
We examined the current studies on the efficiency and effectiveness of the robot interventions and produced a taxonomy of the review. An original finding of the current robotics in rehabilitation landscaping are critical presented with recommendations and concluding remarks concerning interdisciplinary impact. PMID: 32067201 [PubMed - in process]
Conclusion: VR appears to be a promising therapeutic technology for UL motor rehabilitation in patients with stroke. PMID: 32064964 [PubMed - as supplied by publisher]
Conclusion: Prolactin is able to ameliorate ischemia-reperfusion injury in rat brain and might be a potent candidate for further neuro-therapeutics development. PMID: 32064956 [PubMed - as supplied by publisher]
CONCLUSIONS: Health care professionals should assess family functioning after stroke in both patients and their partners, and any discrepancies should be discussed with both members of the patient-partner dyad. PMID: 32064947 [PubMed - as supplied by publisher]
Publication date: Available online 19 February 2020Source: Neuroscience ResearchAuthor(s): Kimihiko Mori, Kae Nakamura, Shingo Hashimoto, Masanori Wakida, Kimitaka HaseAbstractVisual vertical (VV), visually perceived direction of gravity, is widely measured to assess the vestibular function and visuospatial cognition. VV has been assessed by comparing orientation and variability of measured values separately between subject groups. However, changes in orientation and variability often differ in patients with unilateral spatial neglect (USN). Here, we developed a novel classification of VV that combines orientation and vari...
In this study, mice were subjected to 60 minutes of cerebral ischemia followed by reperfusion. The SR protocol was accomplished by depriving mice of sleep for 20 hours/day for 14 days starting at 14 days post-ischemia. We found that SR increased CD169+ macrophages infiltration into the ischemic brain parenchyma and inhibited neurogenesis and functional recovery. SR decreased CD169+ macrophages infiltration into the choroid plexus (CP) and cerebrospinal fluid (CSF), accompanied by increased expression of Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) and intercellular adhesion molecule (ICAM-1) via IFN-γ/IFN-γR signal...
This study shows a meaningful idea of the utilization of the asymmetrical trapezoid flexure mechanism for the design of novel piezoelectric actuators.Graphical Abstract