A novel GnRH-antagonist protocol by switching to medroxyprogesterone when patients being at risk of ovarian hyperstimulation syndrome during ovarian stimulation.

CONCLUSION: This study showed that MPA could sequentially replace GnRHant and effectively prevent premature LH surge after several days of GnRHant administration in patients being at high risk of OHSS during controlled ovarian stimulation. Switch protocol could individualize freeze-all policy and reduce the injection burden of GnRHant.
PMID: 31969249 [PubMed - as supplied by publisher]

Source: J Formos Med Assoc - January 18, 2020 Category: General Medicine Authors: Huang TC, Lin YH, Pan SP, Tu YA, Huang CC, Chen MJ, Hwang JL, Chen SU Tags: J Formos Med Assoc Source Type: research