Significance of TIM-3 Expression in Resected Esophageal Squamous Cell Carcinoma

ConclusionsPositive TIM-3 expression was associated with PD-1 positivity and high CD8+ TILs density, which was an independent risk factor for RFS and OS in ESCC. Furthermore, the combination of TIM-3 and/or PD-1 expression or CD8+ TILs density could further stratify patients into different groups with distinct prognosis.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research