CDKN1B Deletions are Associated with Metastasis in African American Men with Clinically Localized, Surgically Treated Prostate Cancer.

CONCLUSIONS: Overall, PGA, somatic TP53 mutations, and a novel finding of deep deletions in CDKN1B were associated with poor prognosis in AA men. These findings require confirmation in additional AA cohorts.
PMID: 31969336 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - January 21, 2020 Category: Cancer & Oncology Authors: Faisal FA, Murali S, Kaur H, Vidotto T, Guedes LB, Correia Salles D, Kothari V, Tosoian JJ, Han S, Hovelson DH, Hu K, Spratt DE, Baras AS, Tomlins SA, Schaeffer EM, Lotan TL Tags: Clin Cancer Res Source Type: research