Bilateral Renal Agenesis: Redefining Pediatric Palliative Care Across an Innovative Complex Chronic Care Continuum (TH319)

Bilateral renal agenesis has historically been described as “incompatible with life” as chronic anhydramnios results in pulmonary hypoplasia, leading to respiratory failure at birth. Recent reports have detailed the survival of infants with renal disease and severe oligo-/anhydramnios following prenatal serial amnioinfusions as a bridge to neonatal dialy sis with the goal of pediatric kidney transplant. Subsequently, clinical trials have proposed treating fetuses with bilateral renal agenesis with serial prenatal amnioinfusions to allow for pulmonary maturation and the potential for long-term survival.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research