All in the Family: What the Palliative Care Specialist Should Know About Esketamine (FR439)

Depression is common in hospice and palliative care populations, with prevalence's ranging from 17% in the palliative care population and upwards of 40% in hospice patients. Depressive disorders such as major depression frequently go unrecognized and undertreated. Consequences of depressive illness include worsening of quality of life, creation of disability and added symptom burden. Limitations of currently available antidepressant therapies include delayed onset of efficacy and low remission rates after multiple courses of pharmacotherapy.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research

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Conclusion: These findings support the hypothesis that in FM a deteriorated function of cortical inhibition, indexed by a higher SICI parameter, a lower function of the DPMS, together with a higher level of BDNF indicate that FM has different pathological substrates from depression. They suggest that an up-regulation phenomenon of intracortical inhibitory networks associated with a disruption of the DPMS function occurs in FM. Introduction Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Conclusions: From the interviews of the clinicians, we can conclude that care of a stroke patient is more than medical management and rehabilitation, as several other aspects of the patient's life are affected by the condition. The quality of life aspect has to be looked upon as an area that requires active intervention in a setting of stroke. Physical disabilities were viewed as the most significant factor in reducing the quality of life. Spiritual needs have a low priority in comparison to other physical needs. Due to high patient load and time constraints, many of the needs are unaddressed. Two important areas where...
Source: Indian Journal of Palliative Care - Category: Palliative Care Authors: Source Type: research
Authors: Ecenarro PS, Iguiñiz MI, Tejada SP, Malanda NM, Imizcoz MA, Marlasca LA, Navarrete BA Abstract Chronic obstructive pulmonary disease is progressive and in its advanced stage is associated with major disability. Previous studies suggest that patients with this disease receive little palliative care, even in very advanced stages. Given this, our objectives were to describe the clinical practice of Spanish pulmonologists in the care of patients with end-stage chronic obstructive pulmonary disease, to identify potential barriers to implementing palliative care in these patients and to correlate these re...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research
Depression is common in the hospice and palliative care population, with prevalence estimates ranging from 17% in the palliative care population to up to 40% in hospice patients. Depressive disorders such as major depression frequently go unrecognized or undertreated, and are associated with significant disability, impaired quality of life, and increased healthcare utilization. Depression is also associated with poor symptom control and often affects pain, appetite, and motivation. Several studies now provide evidence of ketamine hydrochloride ’s ability to produce rapid and robust antidepressant effects in patients ...
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
This is the 1000th presentation to my bioethics blog since starting on Google in 2004.There has been many topics covered. Though comments by the visitors has always been encouraged and, since as a " discussion blog " , comments leading to discussions I have felt was the definitive function here. Virtually none of the thread topics have gone unread and most have had some commentary, some with mainly particularly strong and emphatic opinions, some with extensive up to 12 years long continued discussion http://bioethi...
Source: Bioethics Discussion Blog - Category: Medical Ethics Source Type: blogs
Conclusion According to the results of the present study, providing non-specific and temporary services is one of the factors affecting the life processes of children who have survived the Manjil earthquake. Training aid workers to consider the specific needs of children at the time of rescue operations could contribute to improving the health of this group in different aspects. Considering effective and comprehensive rehabilitation programs in Disaster Management policymaking can prevent persistent complications caused by earthquakes and other natural disasters. The results of this study also showed that some of the facto...
Source: PLOS Currents Disasters - Category: Global & Universal Authors: Source Type: research
In conclusion, we found that IS status was associated with a significant increase in Hannum DNA methylation, likely as a consequence of the accumulation of cardiovascular risk factors, and near signification with Horvath method. Patients with IS were biologically older than controls, a difference that was more obvious in young stroke. This could open up the possibility of useful new biomarker of stroke risk. Latest Headlines from Fight Aging! A Profile of Kelsey Moody and Ichor Therapeutics
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion. The MUHC interdisciplinary approach to cancer pain management provides meaningful relief of pain and other cancer-related symptoms and decreases patients' disability. PMID: 27445602 [PubMed - in process]
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
CONCLUSIONS: This innovative clinic delivers high levels of patient and provider satisfaction along with time and money savings. We are pursuing further outcome studies to identify medical benefits.Disclosure: Dr. Tuck has nothing to disclose. Dr. Mann has nothing to disclose. Dr. Borcich has nothing to disclose. Dr. Wilhelm has nothing to disclose. Dr. Bryans has nothing to disclose. Dr. Carter has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Pain and Palliative Care Source Type: research
This study aimed to determine if there is a difference between prescription of strict splint wear compared to selective splint wear in patients with de Quervain tendinopathy. We tested the primary null hypothesis that there is no difference in upper-extremity disability eight weeks after initiating splinting between patients prescribed full-time or as-desired splint wear. Secondary study questions addressed differences in grip strength, pain intensity, and treatment satisfaction. Additionally, we evaluated the influence of psychological factors on disability. Methods Eighty-...
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
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