P078 donor selection influences therapeutic effects of fecal microbiota transplantation for ulcerative colitis

We have recently reported the efficacy of combination of triple-antibiotic therapy and fecal microbiota transplantation (A-FMT) for patients with ulcerative colitis (UC). It has been reported that FMT with frozen donor faeces (frozen-FMT) is as effective as fresh-FMT for Clostridium difficile infection. However, it is still unclear which donor and condition is suitable for FMT on UC. The aim of this study was to evaluate the effectiveness of frozen-FMT compared to fresh-FMT, and verify effective conditions.

Source: Gastroenterology - January 25, 2020 Category: Gastroenterology Authors: Keiichi Haga, Dai Ishikawa, Koki Okahara, Kei Nomura, Shoko Ito, Masahito Takahashi, Tomoyoshi Shibuya, Akihito Nagahara Tags: Microbial-Based Therapy Source Type: research