Prostaglandin E2 Affects Interleukin 6 and Monocyte Chemoattractant Protein 1/CCL2 Production by Cultured Stem Cells of Apical Papilla

Root canal treatment of immature necrotic teeth is a major challenge in current endodontics. The effect of inflammatory mediators, such as prostaglandin, on the modulation of stem cells of the apical papilla (SCAP) is not completely understood. The aim of this study was to investigate the role of prostaglandin E2 (PGE2) on SCAP activation by Escherichia coli lipopolysaccharide (LPS) in  vitro.

Source: Journal of Endodontics - January 23, 2020 Category: Dentistry Authors: Claudia Caroline Bosio Meneses, Lais Nicolay Pizzatto, Fernanda Fachini Feres Andrade, Carla Renata Sipert Tags: Basic Research Source Type: research