[ASAP] Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01769

Source: Journal of Medicinal Chemistry - January 24, 2020 Category: Chemistry Authors: Dongwei Kang †?, F. Xavier Ruizf|, Da Feng†, Alyssa Pilchf|, Tong Zhao†, Fenju Wei†, Zhao Wang†, Yanying Sun†, Zengjun Fang?, Erik De Clercq§, Christophe Pannecouque§, Eddy Arnold*f|, Xinyong Liu*†, and Peng Zhan*† Source Type: research