Long term outcomes of abdominal wall reconstruction using open component separation and biologic mesh in the liver, kidney, and small bowel transplant population
ConclusionModified open CST with biologic mesh is a safe, efficacious approach to complex AWR in the SOT population with recurrence rates comparable to the general population.
ConclusionOur analysis provided strong evidence to indicate a causal relationship between WC and increased risk of CHD.
ConclusionOur results suggest that the combination of altered expression of genes involved in signaling pathways of immune response and apoptosis control may contribute directly to the main characteristics observed in BS, such as recurrent infections, growth failure, and high risk of cancer. Transcriptome studies of other instability syndromes could allow a more accurate analysis of the relevant gene interactions associated with the destabilization of the genome. This is a first description of the profile of differential gene expression related to immunological aspects detected in patients with BS by RNA ‐seq.
Publication date: Available online 27 February 2020Source: The American Journal of SurgeryAuthor(s): Lawrence A. Lavery, Kathryn E. Davis, Javier La Fontaine, J. David Farrar, Kavita Bhavan, Orhan K. Oz, Peter A. Crisologo
The objective of this study was to examine the effect of metabolic syndrome on 30-day postoperative complications following corrective surgery for the adult spinal deformity (ASD). Summary of Background Data: Metabolic syndrome has been shown to increase the risk of cardiovascular morbidity and mortality. Few studies have examined the effect of metabolic syndrome on patients with ASD undergoing surgery. Materials and Methods: We performed a retrospective cohort study of patients who underwent spinal fusion for ASD. Patients were divided into 2 groups based on the presence or absence of metabolic syndrome, which was d...
This study examined surgically diagnosed aortitis and identified patient characteristics and imaging findings associated with the disease.MethodsIn this case ‐control study, cases had biopsy proven, newly‐diagnosed, non‐infectious aortitis following open thoracic aortic aneurysm surgical repair. Five controls were matched by year of surgery and lacked significant inflammation on pathology. Comorbidities, demographics, laboratory, and imaging abnorm alities prior to surgery were collected. Associations between exposures and outcomes were evaluated using conditional logistic regression. Backward stepwise logistic regre...
Publication date: Available online 26 February 2020Source: Journal of Advanced ResearchAuthor(s): Heng Zhang, Yaqian Huang, Selena Chen, Chaoshu Tang, Guang Wang, Junbao Du, Hongfang Jin
Conditions: Diabetes Mellitus; Cardiovascular Diseases Interventions: Drug: Renin-angiotensin-aldosterone system inhibitors; Drug: Beta blocker; Drug: SGLT2 Inhibitor - Sodium Glucose Cotransporter Subtype 2 Inhibitor Product Sponsors: National Heart Centre Singapore; Singapore General Hospital; Mackay Memorial Hospital; National Taiwan University Hospital; Peking University People's Hospital; Medanta, The Medicity, India; Public Health&...
Conditions: Diabetes Mellitus, Type 2; Diabetes; Diabetes type2; Type2 Diabetes; Type 2 Diabetes; Type II Diabetes; Hypertension; High Blood Pressure Interventions: Other: DASH4D diet; Other: comparison diet; Other: higher sodium; Other: lower sodium Sponsors: Johns Hopkins University; Beth Israel Deaconess Medical Center Not yet recruiting
Condition: Pre-Diabetic Interventions: Drug: Calcitriol capsules; Drug: Oral Placebo Sponsor: Mayo Clinic Not yet recruiting
CONCLUSIONS: This small, retrospective series of complex open CST in transplant patients shows acceptable rates of long-term hernia recurrence and healing. By using a multidisciplinary approach for abdominal wall reconstruction, we believe that modified open CST with biologic mesh is a safe and effective technique in the transplant population with complex abdominal hernias. PMID: 31550752 [PubMed]