Prognostic Impact of Pre-Transplant Chromosomal Aberrations Detected By SNP-Array in Patients Undergoing Unrelated Donor Hematopoietic Cell Transplant for Acute Myeloid Leukemia

High-resolution genome-wide SNP-arrays detect large chromosomal aberrations including copy-neutral loss of heterozygosity (CNLOH), which is not captured in conventional cytogenetics.

Source: Biology of Blood and Marrow Transplantation - January 24, 2020 Category: Hematology Authors: Youjin Wang, Weiyin Zhou, Lisa J. McReynolds, Elizabeth A Griffiths, Swapna Thota, Mitchell J. Machiela, Stephen J Chanock, Meredith Yeager, Philip L. McCarthy, Marcelo C. Pasquini, Junke Wang, Ezgi Karaesmen, Abbas Rizvi, Leah Preus, Hancong Tang, Yiwen Tags: 13 Source Type: research