Patient Discharge Process Following Immune Effector Cell Therapy

A Comprehensive Cancer Center (CCC) providing cellular immunotherapy treatments developed a standardized discharge process to ensure optimal continuity of care following immune effector cell (IEC) therapy. As utilization of IEC therapies increases, it is imperative to have an outlined comprehensive discharge plan to promote continuity of care, treatment-specific follow up, and ensure both patient and referring provider feel confident to assume follow-up care. Nurses are pivotal to this process development and implementation.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 585 Source Type: research

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CONCLUSIONS: SIR-Spheres Y-90 resin microspheres resulted in cost savings relative to TKIs in the treatment of unresectable HCC in all four country settings, while increasing the proportion of patients who become eligible for treatments with curative intent. PMID: 32067534 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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Source: Fight Aging! - Category: Research Authors: Tags: Healthy Life Extension Community Source Type: blogs
Authors: Okan Cakir M, Kirca O, Gunduz S, Ozdogan M Abstract Infections in immunocompromised-neoplastic patients represent a severe complication. Among bacteria, Enterococcus species constitute a common causative pathogen of urinary tract infections (UTIs), especially among hospitalized patients with or without urinary tract carcinoma, related commonly to urinary tract abnormalities, urinary catheters or prolonged antibiotic treatment. Although enterococci have been considered more commonly as colonization bacteria in the intestine than virulent agents, they are frequently implicated in UTIs. The high incidence of ...
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
Hematological malignancies have long been at the forefront of the development of novel immune-based treatment strategies. The earliest successful efforts originated from the extensive body of work in the field of allogeneic hematopoietic stem cell transplantation. These efforts laid the foundation for the recent exciting era of cancer immunotherapy, which includes immune checkpoint blockade, personal neoantigen vaccines, and adoptive T cell transfer. At the heart of the specificity of these novel strategies is the recognition of target antigens presented by malignant cells to T cells. Here, we review the advances in system...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Delivery of cellular immunotherapy (IMTX) in the ambulatory setting continues to evolve in an academic Comprehensive Cancer Center. A dedicated IMTX outpatient department (OPD) was opened in 2016 (patients treated=427), providing both FDA approved CAR T cell and phase l/ll immune effector cell treatments. Provision of care to acutely ill patients, ensuring early recognition of treatment related side effects, and triggering a prompt hospitalization when indicated, requires an intricate triage system.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 590 Source Type: research
Early detection of neurotoxicity (NT) and prompt intervention in patients receiving cellular immunotherapy products is crucial. Guidance on the type of neurologic assessment to be conducted has only recently been established. Previously inconsistent and infrequent assessments varied from institution and depended upon individual nurses ’ clinical experience with NT.  “ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells” was published in 2018 and a plan for implementation of a standardized NT nursing assessment was needed at a Comprehensiv...
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 586 Source Type: research
In 2016, a Comprehensive Cancer Center opened an ambulatory cellular immunotherapy clinic, partnered with an inpatient facility for hospitalization. The center provides FDA Approved CAR T Cell therapies as well investigational immune effector cell (IEC) products under Phase I/II clinical trials. To optimize patient care, a multidisciplinary workgroup developed IEC specific standard of care guidelines. These standards facilitate alignment of care between sites and promotes collaboration between nurses and providers to enhance patient outcomes.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 600 Source Type: research
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Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 333 Source Type: research
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