Efficacy and Safety of Sedo-Anesthesia in Autologous Stem Cells Transplantation in Children with Cerebral Palsy or Autism: Propofol Following Sevoflourane Inhalation

Intrathecal autologous bone marrow (ABM) total nucleated cells transplantation (TNCT) has been reported to be a promising treatment for cerebral palsy (CP) and autistic disorders (AD). Children with CP and AD, are expected to be patients with difficult approach when doing venipuncture or taking them to the operating room. Considering pain and the nature of the procedures, bone marrow collection (BMC) and intrathecal procedures (ITP) must be performed under sedation. For short procedures, sevoflurane can be administrated using a face mask and, propofol, a typical intravenous agent is used for the induction of general anesthesia and for sedation.

Source: Biology of Blood and Marrow Transplantation - January 24, 2020 Category: Hematology Authors: Ileana Velasco-Ruiz, Jose Luis Guerrero-Gonzalez, Antonio Ioshy Valencia-Alcocer, Jane Citlaly Lopez-Quezada, Carlos de La Cruz-De La Cruz, Sofia Alejandra Carre ño-Salcedo, Jennifer Gonzalez-Ramirez, Consuelo Mancias-Guerra, Cesar Homero Gutierrez-Aguir Tags: 419 Source Type: research