Development of the Renal Adjusted Hematopoietic Cell Transplant Comorbidity Index (RA-HCT-CI) Using Different Levels of Renal Dysfunction According to Estimated Glomerular Filtration Rate (eGFR)

Chronic kidney disease (CKD) is a known risk factor for post-HCT mortality. Currently, HCT-CI assigns a score of 2 for moderate-severe renal dysfunction based on serum creatinine (Cr), though Cr is not ideal marker of renal function and can be influenced by several factors. The aim of this study is to examine whether utilization of incremental degrees of renal dysfunction based on eGFR improves the utility of HCT-CI to predict allogeneic HCT outcomes.

Source: Biology of Blood and Marrow Transplantation - January 24, 2020 Category: Hematology Authors: Nosha Farhadfar, Hemant Murthy, Tao Wang, Caitrin Fretham, Ajoy Dias, Brent Logan, Shin Mineishi, Bipin Savani, Edward A. Stadtmauer, Saurabh Chhabra, Siddhartha Ganguly, John R. Wingard, Marcelo C. Pasquini Tags: 189 Source Type: research