Lp(a) and Apo-lipoproteins as predictors for diabetic retinopathy and its severity in patients with type 2 diabetes: A case-cohort study

Publication date: Available online 23 January 2020Source: Canadian Journal of DiabetesAuthor(s): Fatemeh Moosaie, Reza Mohamadhosseinzadeh Davatgari, Fatemeh Dehghani Firouzabadi, Sadaf Esteghamati, Niloofar Deravi, Alipasha Meysamie, Pegah Khaloo, Manouchehr Nakhjavani, Alireza EsteghamatiAbstract:AimsTo measure the relationship between serum Lp(a) and apolipoproteins and the risk of developing diabetic retinopathy(DR)Methods1057 patients with type 2 diabetes were divided into three groups and followed for five years: 637 patients without DR, 162 patients with non-proliferative DR (NPDR), and 163 patients with proliferative DR (PDR). The association between serum Lp (a) and apolipoproteins with NPDR and PDR was assessed by using univariate and multivariate regression analysis. The ROC analysis was measured based on the new cutoff values.ResultsThere was a positive relationship between Lp(a) and the presence of DR as well as a negative correlation between ApoA and DR (p value
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research

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