Radiation dose-painting with protons vs. photons for head-and-neck cancer.
Conclusion: Proton dose-painting for HNC seems feasible and can reduce the non-target dose overall, however not significantly to certain organs close to the target, such as the salivary glands. Max dose in proton plans had a lower robustness compared to photons, requiring caution to avoid unintended hot spots in consideration of the risk of mucosal toxicity.
PMID: 31964199 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: HÃ¥kansson K, Smulders B, Specht L, Zhu M, Friborg J, Rasmussen JH, Bentzen SM, Vogelius IR Tags: Acta Oncol Source Type: research
More News: Cancer | Cancer & Oncology | Head and Neck Cancer | Hypopharyngeal Cancer | Laryngeal Cancer | Oropharyngeal Cancer | Proton Therapy | Toxicology