Atypical radiological manifestations of thoracic sarcoidosis: A review and pictorial essay

We present a review of literature and illustrate the review with unpublished data, intended to provide a more recent single comprehensive reference to assist with the diagnosis when atypical radiographic findings of thoracic sarcoidosis are encountered. Thoracic involvement accounts for most of morbidity and mortality associated with sarcoidosis. An accurate timely identification is required to minimize morbidity and mortality. It is essential to recognize atypical imaging findings and relate these to clinical manifestations and histology.
Source: Annals of Thoracic Medicine - Category: Respiratory Medicine Authors: Source Type: research

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ConclusionsThis study provided useful information that the relapse and associated risk factors should be taken into considerations when determining treatment strategies for patients with pulmonary sarcoidosis.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Conclusions: Pseudomeningoceles following ONSF may be asymptomatic or may cause symptomatic orbital mass effect and rarely visual loss, amendable to surgical excision. Post-ONSF pseudomeningoceles are identified on computed tomography or magnetic resonance imaging to occur at the locations of fenestration sites and contain cerebrospinal fluid communicating with the subdural space that may act as a “filtration” bleb in some cases. Imaging findings may represent a spectrum spanning intraorbital cerebrospinal fluid leakage, partial walling off of bleb, or fully developed cysts. Resection of optic nerve pseudomen...
Source: Ophthalmic Plastic and Reconstructive Surgery - Category: Opthalmology Tags: Original Investigations Source Type: research
Discussion Barth syndrome is characterized by a dilated cardiomyopathy, proximal skeletal muscle weakness, neutropenia and short stature that usually presents at birth or soon after. It is a rare X-linked recessive disease process caused by mutations in the TAZ gene. The TAZ gene codes for tafazzin which alters cardiolipin in mitochondria. Characteristic facies can be seen especially in infancy including a tall and broad forehead, prominent chin and full cheeks, larger ears, and deep-set eyes. Most patients present at birth or soon afterwards but some may not until later in life. Life expectancy is reduced with many childr...
Source: - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
ConclusionAbdominal irAEs were detected on CT in 13% of NSCLC patients treated with nivolumab, and colitis, in the pancolitis form, was the most common irAE. Given the expanding role of immunotherapy, radiologists should be aware of the frequency and imaging manifestations of abdominal irAEs and the impact on patient management.
Source: Abdominal Imaging - Category: Radiology Source Type: research
AbstractPurpose of ReviewThe purpose of this review article is to present the spectrum of abnormalities and multi-modality imaging evaluations in patients with musculoskeletal sarcoidosis.Recent FindingsThe articular manifestations of sarcoidosis are difficult to distinguish from those of the other inflammatory and degenerative arthropathies, and the muscular lesions in sarcoidosis are generally clinically silent and therefore often missed. Magnetic resonance imaging has shown these manifestations to be very common in active sarcoidosis, and should thus be included in the screening if musculoskeletal sarcoidosis is suspect...
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research
In this article, we present a unique case of active pulmonary tuberculosis, with multiple huge “cluster” signs like fireworks, together with multiple “galaxy” signs. The repeated acid‐fast sputum smears and both bronchial washings were all negative forMycobacterium tuberculosis, but the acid ‐fast culture of sputum taken soon after the first bronchoscopy, and pleural fluid, turned out to be positive forM. tuberculosis at six weeks after admission. The present case clearly demonstrates that the “galaxy” and “cluster” signs are red herring signs of the low rates of isolatin...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
Publication date: Available online 4 January 2019Source: Seminars in Ultrasound, CT and MRIAuthor(s): Arya M. Iranmanesh, Lacey WashingtonAbstractSarcoidosis is a multisystem granulomatous process that most commonly involves the lungs. Radiographic findings consistent with sarcoidosis are important to the diagnosis of this disease, as no specific diagnostic test for sarcoidosis exists. The classic imaging manifestations of sarcoidosis are related to granulomatous involvement along the lymphatic pathways within the lungs, granulomatous involvement of lymph nodes, and fibrosis at the sites of previous inflammation. These fin...
Source: Seminars in Ultrasound, CT and MRI - Category: Radiology Source Type: research
Background: The ATS/ERS guideline definition of obstructive pattern in lung function tests does not consider measurement of static lung volumes as mandatory.Methods: Patients with pulmonary sarcoidosis (n=1110; 529 males) were enrolled. Static volumes expected in association with an obstructive process was quantified in a control cohort of COPD patients (n=899; 536 males). Ventilatory defects in sarcoidosis patients, were defined according to ATS/ERS and with the reclassification of a sub-group of patients from obstructive to mixed disease, based on TLC values below those expected in the control COPD cohort.Results: A prev...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research
This study aimed to evaluate the aforementioned tests, in order to examine the functional capacity of sarcoidosis patients, in different stages.Methods: This cross-sectional study carried out, on 50 Iranian patients with sarcoidosis. Patients were classified into three groups, based on the findings of the chest radiography, as well as the pulmonary CT scan, performed by an expert Radiologist; Pulmonary, cardiac and activity function have been evaluated in the patients, using CPET, 6MWT and spirometry.Results: In CPET, percent-predicted peak VO2, 57.75±15.49, p
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research
Conclusion: The pathology discovered after many years indicates the need for an expanded involvement of specialists in primary and dynamic examination of patients with sarcoidosis.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sarcoidosis and other granulomatous ILD/DPLD Source Type: research
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