Dust in home may be spreading SUPERBUGS by carrying genes that give antibiotic resistance

Scientists at Northwestern University in Illinois studied 166 indoor dust samples and found that bacteria living within them were able to share antibiotic resistant genes with each other.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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AbstractBackgroundTo assess the in-vitro efficacy of delafloxacin, a new fourth generation fluoroquinolone, againstStaphylococcus vitreous isolates from patients with clinically diagnosed endophthalmitis. This is the first investigation of delafloxacin in ocular tissues.MethodsIntravitreal isolates of culture-provenS. aureus andS. epidermidis were identified between 2014 and 2018. Minimum inhibitor concentrations (MIC) were determined using ETEST strips. The antibiotic susceptibilities were tested against a panel of drugs including glycopeptides such as vancomycin, as well as traditional and newer fluoroquinolones (levoflo...
Source: Journal of Ophthalmic Inflammation and Infection - Category: Opthalmology Source Type: research
Conclusion: The increase in antibiotic resistance and beta-lactamase production in M. catarrhalis is a cause of concern. The emerging resistance pattern emphasises the need for an appropriate antibiotic stewardship program in clinical practice. Importance should be given to the monitoring of the trends of antibiotic susceptibility and their usage to prevent the emergence of outbreaks with resistant strains and treatment failures.M. catarrhalis was noted in 1977 in Sweden. This has gradually spread worldwide over the years to more than 95% of the strains showing resistance to penicillin now. Penicillin resistance is mediate...
Source: International Journal of Microbiology - Category: Microbiology Tags: Int J Microbiol Source Type: research
(McMaster University) The research team found that CBG had antibacterial activity against drug-resistant MRSA. It prevented the ability of that bacteria to form biofilms, which are communities of microorganisms that attach to each other and to surfaces; and it destroyed preformed biofilms and cells resistant to antibiotics. CBG achieved this by targeting the cell membrane of the bacteria. These findings in the laboratory were supported when mice with an MRSA infection were given CBG.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
(University of Utah Health) Doctors who use drugs that target antibiotic-resistant bacteria as a first-line defense against pneumonia should probably reconsider this approach, according to a new study of more than 88,000 veterans hospitalized with the disease. The study, conducted by University of Utah Health and VA Salt Lake City Health Care System researchers, found that pneumonia patients given these medications in the first days after hospitalization fared no better than those receiving standard medical care for the condition.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(American Chemical Society) Public health agencies worldwide have identified antibiotic resistance of disease-causing bacteria as one of humanity's most critical challenges. However, scientists haven't discovered a new class of antibiotics in more than 30 years. Now, researchers reporting in ACS Infectious Diseases have uncovered the hidden antibiotic potential of a non-psychoactive cannabis compound called cannabigerol (CBG), which helped control methicillin-resistant Staphylococcus aureus (MRSA) infections in mice.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
IJERPH, Vol. 17, Pages 1500: Assessing the Potential Impact of a Long‐Acting Skin Disinfectant in the Prevention of Methicillin‐ Resistant Staphylococcus aureus Transmission International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17051500 Authors: Short Mietchen Lofgren Healthcare‐associated transmission of methicillin‐resistant Staphylococcus aureus (MRSA)remains a persistent problem. The use of chlorhexidine gluconate (CHG) as a means of decolonizingpatients, either through targeted decolonization or daily bathing, is frequently used to supplementother interventions. ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
ConclusionThere was a significant association of antibiotic therapy and age on S. aureus carriage profiles in CF patients indicating that antibiotic therapy prevents acquisition of new clones, while during aging of patients with persisting S. aureus, dominant clones were selected and mutations in the spa-repeat region accumulated.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
AbstractReduction in diversity of the intestinal microbiome (dysbiosis) is being identified in many disease states, and studies are showing important biologic contributions of microbiome to health and disease. Fecal microbiota transplantation (FMT) is being evaluated as a way to reverse dysbiosis in diseases and disorders in an attempt to improve health. The published literature was reviewed to determine the value of FMT in the treatment of medical disorders for which clinical trials have recently been conducted. FMT is effective in treating recurrentC. difficile infection in one or two doses, with many healthy donors prov...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Abstract Prosthetic joint infection (PJI) is one of the most devastating failures in total joint replacement (TJR). Infections are becoming difficult to treat due to the emergence of multi-drug resistant bacteria. These bacteria produce biofilm on the implant surface, rendering many antibiotics ineffective by compromising drug diffusion and penetration into the infected area. With the introduction of new antibiotics there is a need to create benchmark data from the traditional antibiotic loaded bone cements. Vancomycin, one of the commonly used antibiotics, shows activity against Methicillin-resistant Staphylococc...
Source: Journal of the Mechanical Behavior of Biomedical Materials - Category: Materials Science Authors: Tags: J Mech Behav Biomed Mater Source Type: research
TUESDAY, Feb. 25, 2020 -- Common heartburn meds may foster the growth of antibiotic-resistant bacteria in the gut, a new research review suggests. In an analysis of 12 past studies, researchers found that, overall, the evidence supports a link:...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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