A pharmacological chaperone improves memory by reducing A β and tau neuropathology in a mouse model with plaques and tangles

The vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex system, an ubiquitous multiprotein assembly responsible for sorting and trafficking protein cargos out of the endosomes. VPS...

Source: Molecular Neurodegeneration - January 22, 2020 Category: Neurology Authors: Jian-Guo Li, Jin Chiu, Mercy Ramanjulu, Benjamin E. Blass and Domenico Pratic ò Tags: Research article Source Type: research