Newer Insights Into Takotsubo Cardiomyopathy

We congratulate Auger et al for their study on takotsubo cardiomyopathy.1
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: LETTER Source Type: research

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Conclusions: Our study showed that NLVS defines a group of systolic HF patients which not only did not have less severe disease than those with enlarged left ventricules (i.e., DCM), also had more HF rehospitalization. These NLVS patients also had steady clinical, laboratory, and echocardiographic profile during follow-up.
Source: Critical Pathways in Cardiology - Category: Cardiology Tags: Original Articles Source Type: research
(Mayo Clinic) An approach based on artificial intelligence (AI) may allow EKGs to be used to screen for hypertrophic cardiomyopathy in the future. With hypertrophic cardiomyopathy, the heart walls become thick and may interfere with the heart's ability to function properly. The disease also predisposes some patients to potentially fatal abnormal rhythms. Current EKG technology has limited diagnostic yield for this disease.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Subcutaneous implantable cardioverter defibrillators (S-ICD) are attractive for preventing sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) as they mitigate risks of transvenous leads in young patients. However, S-ICDs may be associated with increased inappropriate shock (IAS) in HCM patients.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
Myocardial autophagy has been recognized as an important factor in heart failure. It is not known whether changes in ventricular geometry by left ventriculoplasty influence autophagy in ischemic cardiomyopathy. We hypothesized that myocardial autophagy plays an important role in left ventricular (LV) redilation after ventriculoplasty.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
Conditions:   Pacemaker DDD;   Atrioventricular Block;   Pacing-Induced Cardiomyopathy Intervention:   Device: Right ventricular pacing Sponsors:   Aalborg University Hospital;   Svend Andersens Foundation;   Peacs;   Aalborg University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study aims to compare the clinical course of peripartum cardiomyopathy (PPCM) cohorts from Germany (G ‐PPCM) and South Africa (SA‐PPCM) with fibrosis‐related markers to get insights into novel pathomechanisms of PPCM.Methods and resultsG ‐PPCM (n = 79) and SA ‐PPCM (n = 72) patients and healthy pregnancy ‐matched women from Germany (n = 56) and South Africa (n = 40) were enrolled. Circulating levels of procollagen type ‐I (PINP) and type‐III (PIIINP) N‐terminal propeptides, soluble ST2, galectin‐3, and full‐length and cleaved osteopontin (OPN) were measured at diagnosis (baseline) and 6 months of...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
ConclusionsSubstantial recovery of LV function occurs within 12  months in most patients with recent‐onset DCM. Women had the greatest improvement in LVEF. A low LV contractile reserve measured by dobutamine stress CMR appears to identify patients whose LVEF is less likely to recover.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
CONCLUSIONSIn patients with NICM, lower sMBF predicts VA. This relationship may be useful for risk stratification for ventricular arrhythmia and decision ‐making regarding ICD implantation.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conclusions: This retrospective registry-based study provides a picture of CIED first implants in HCM patients in a Swedish tertiary university hospital. ICDs were the most commonly implanted devices, covering 59% of CIED implants. HCM patients receiving a pacemaker or an ICD had different epidemiological and clinical profiles. PMID: 32054352 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
In this study, we describe spontaneous lesions found in 39 male RccHan:WIST rats used as a control in a carcinogenicity study. Neoplastic lesions were frequently seen in the endocrine system, such as pituitary adenomas in the pars distalis. This strain exhibited a high incidence of thymoma (10.3%), compared to other strains. We encountered an oligodendroglioma, a pituitary adenoma of the pars intermedia, and a prostate adenocarcinoma, which are comparatively rare in rats. While the variety and incidence of non-neoplastic lesions were similar to those in other strains, several interesting lesions occurred with relatively hi...
Source: Journal of Toxicologic Pathology - Category: Toxicology Tags: J Toxicol Pathol Source Type: research
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