A Zika vaccine could save suffering and costs

(CUNY Graduate School of Public Health and Health Policy) A new study led by researchers at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH) and the National School of Tropical Medicine at Baylor College of Medicine found that routinely giving the Zika vaccine to women of childbearing age could save money if the risk of Zika is around that of other mosquito-borne diseases like dengue and chikungunya.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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Viruses transmitted by Aedes mosquitoes, such as dengue, Zika, and chikungunya, have expanding ranges and seem unabated by current vector control programs. Effective control of these pathogens likely requires integrated approaches. We evaluated dengue management options in an endemic setting that combine novel vector control and vaccination using an agent-based...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
Canadian Journal of Microbiology, e-First Articles. Zika virus (ZIKV) is a mosquito-borne virus that was first isolated from Zika forest, Uganda, in 1947. Since its inception, major and minor outbreaks have been documented from several parts of world. Aedes spp. mosquitoes are the primary vectors of ZIKV, but the virus can also be transmitted through sexual practices, materno-fetal transmission, and blood transfusion. The clinical presentations of symptomatic ZIKV infections are similar to dengue and chikungunya, including fever, headache, arthralgia, retro-orbital pain, conjunctivitis, and rash. ZIKV often causes mild ill...
Source: Canadian Journal of Microbiology - Category: Microbiology Authors: Source Type: research
Source: World Health Organization, Pan American Health Organization (PAHO). Published: 10/9/2019. This 60-page manual provides technical guidelines for the strategic use of indoor residual spraying for Aedes aegypti mosquito control (IRS-Aedes) in urban areas, and compiles and standardizes the criteria, instruments, technical parameters, and equipment, as well as the application technique, for strategic integration of IRS-Aedes in Aedes aegypti control programs. Given the absence of a specific treatment and vaccines against dengue, chikungunya, and Zika, and the limitations of current vector control strategies, the World ...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
Hurricane Dorian’s 185 mph winds and punishingly slow pace smashed entire neighborhoods in the Bahamas, killing at least 50 people. But now, Bahamians are facing a different kind of threat. The lack of access to toilets, clean water and medications puts tens of thousands at risk for disease, public health experts warn. Bahamians in the hardest-hit areas are already suffering from cuts and gashes caused by widespread debris and wreckage. But now aid groups are saying survivors are beginning to show signs of gastrointestinal issues from contaminated water. Those with chronic illnesses are struggling without access to t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Bahamas Infectious Disease onetime weather Source Type: news
Aedes spp. are a major public health concern due to their ability to be efficient vectors of dengue, Chikungunya, Zika and other arboviruses. With limited vaccines available and no effective therapeutic treatments against arboviruses, the control of Aedes spp. populations is currently the only strategy to prevent disease transmission. Host-associated microbes (i.e. microbiota) recently emerged as a promising field to be explored for novel environmentally-friendly vector control strategies. In particular, gut microbiota is revealing its impact on multiple aspects of Aedes spp. biology, including vector competence, thus bein...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
ABSTRACT Measles is an acute febrile exanthematic disease of viral etiology, highly contagious, being the cause of morbidity and mortality of children in developing countries, whereas it has become rarer in developed countries due to vaccination. Its differential diagnosis should be made with other childhood viral respiratory diseases such as influenza, rhinovirus and adenovirus, and exanthematic febrile diseases such as rubella, roseola and varicella. In tropical regions, it should be performed with dengue, zika and chikungunya. Its clinical picture presents the following phases: incubation, usually asymptomatic; a prodro...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research
Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Abstract Mayaro virus (MAYV; family Togaviridae, genus Alphavirus) is an emerging global threat that can cause severe clinical manifestations similar to Zika, dengue, and chikungunya viruses. Currently, there is a lack of molecular tools to enable a better understanding of the transmission and pathogenesis of MAYV. Here, we detail the development and characterization of infectious clones of two strains of MAYV that produce infectious virus and replicate in mammalian and mosquito cells similarly to wild-type virus. Additionally, clone-derived viruses produced identical infection rates and phenotypes in CD-1 mice co...
Source: Virology - Category: Virology Authors: Tags: Virology Source Type: research
Publication date: Available online 29 May 2019Source: International Journal of Pediatrics and Adolescent MedicineAuthor(s): Tracy Evans-GilbertAbstractChikungunya (CHIKV), Zika (ZIKV), and Dengue viruses (DENV) exhibit similar epidemiological and clinical patterns but have different pathophysiological mechanisms of disease manifestations. Differences occur in the severity of clinical presentations with the highest mortality in the general population attributed to DENV and neurological morbidity due to ZIKV. ZIKV and DENV infections can cause fetal loss with ZIKV exhibiting teratogenesis. CHIKV is associated with severe com...
Source: International Journal of Pediatrics and Adolescent Medicine - Category: Pediatrics Source Type: research
Publication date: Available online 29 May 2019Source: International Journal of Pediatrics and Adolescent MedicineAuthor(s): Tracy Evans-GilbertAbstractChikungunya (CHIKV), Zika (ZIKV), and Dengue viruses (DENV) exhibit similar ecological, evolutionary, and epidemiological patterns but have different pathophysiological mechanisms of disease manifestations. Clinical presentations overlap and can be asymptomatic. Differences occur in the severity of clinical presentations with the highest mortality in the general population attributed to DENV and neurological morbidity due to ZIKV. ZIKV and DENV infections can cause fetal los...
Source: International Journal of Pediatrics and Adolescent Medicine - Category: Pediatrics Source Type: research
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