The authors reply: Still much to learn about andexxa alfa in the ED

We appreciate the comments in the letter to the editor regarding our study describing our utilization of andexanet alfa [1]. Of the four patients with an intracranial hemorrhage (ICH) in our study who died, none had hematoma expansion noted on repeat imaging. One patient had a subarachnoid hemorrhage (SAH) with a Modified Fisher score of 4, and the three other patients had an ICH with ICH scores of 4, 3, and 2 respectively. Our results are similar to studies evaluating prothrombin complex concentrate (PCC) for reversal in this patient population which found that PCC did not change clinical outcomes [2,3].
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Correspondence Source Type: research