Revealed an alteration related to the loss of effectiveness of a treatment in lung cancer

(Josep Carreras Leukaemia Research Institute) Researchers from IJC reveal that non-smoking patients with lung cancer that have an alteration in RB1 and are treated with EGFR inhibitors, acquire resistance to treatment through the mechanism of histopathological transformation, either to non-small cell lung cancer (SCLC) or SLCL combined with a transformation to squamous cell lung cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news