Critical Care Management in Patients with Acute Liver Failure
Publication date: Available online 23 January 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Nadja Rifaie, Fuat H. SanerAbstractAcute liver failure is defined as severe hepatic dysfunction (marked transaminases elevation, detoxification disorder (jaundice and coagulopathy with INR> 1.5)Presence of hepatic encephalopathy and exclusion of underlying chronic liver disease and a secondary cause like sepsis or cardiogenic shock.Reasons for acute liver failure includes paracetamol -and warfarin toxicity, autoimmune – and viral (mainly hepatitis B and E) hepatitis, herbal and dietary supplements. Even in term of meticulous and careful review of the patient around 20-30% of the reasons remains unknown. In order of its rarity, randomized controlled trial could hardly be done. However, due to improved ICU treatment, the mortality, even in advanced stage of ALF decreased. However, in 5-10% of the cases an emergency transplantation is required. This justifies the treatment of this patient cohort in institutions who can provide this kind of treatment.
ConclusionOur data indicate that the p.V876E mutation inCACNA1S contributes to the early onset of neuromuscular symptoms and unusual clinical phenotypes of HypoPP.
The objective of this study was to examine the effect of metabolic syndrome on 30-day postoperative complications following corrective surgery for the adult spinal deformity (ASD). Summary of Background Data: Metabolic syndrome has been shown to increase the risk of cardiovascular morbidity and mortality. Few studies have examined the effect of metabolic syndrome on patients with ASD undergoing surgery. Materials and Methods: We performed a retrospective cohort study of patients who underwent spinal fusion for ASD. Patients were divided into 2 groups based on the presence or absence of metabolic syndrome, which was d...
Conditions: HCV; HBV; Hiv Intervention: Procedure: HCV, HBV, HIV tests Sponsors: Assistance Publique - Hôpitaux de Paris; Gilead Sciences Not yet recruiting
Conditions: Anesthesia; Surgery Interventions: Device: I-Gel Laryngeal Mask Airway; Device: Ambu Auragain Laryngeal Mask Airway Sponsor: University of Minnesota Not yet recruiting
Conditions: Diabetes Mellitus, Type 2; Diabetes; Diabetes type2; Type2 Diabetes; Type 2 Diabetes; Type II Diabetes; Hypertension; High Blood Pressure Interventions: Other: DASH4D diet; Other: comparison diet; Other: higher sodium; Other: lower sodium Sponsors: Johns Hopkins University; Beth Israel Deaconess Medical Center Not yet recruiting
Condition: Alcohol-related Liver Disease Intervention: Drug: Acomprosate Sponsor: Mayo Clinic Not yet recruiting
Conditions: Nausea; Vomiting; Anxiety State Intervention: Other: Inhalation aromatherapy with orange essential oil Sponsor: Hacettepe University Completed
Condition: Dyslexia, Developmental Interventions: Dietary Supplement: Poly-unsaturated fatty acids supplementation; Behavioral: Neuropsychological intervention; Dietary Supplement: Placebo Sponsors: IRCCS Eugenio Medea; University of Milan; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Not yet recruiting
Conditions: Neuromuscular Blockade; Intubation Complication; Anesthesia Interventions: Drug: Rocuronium 0.6 mg/kg; Drug: Remifentanil 2 µg/kg Sponsor: Rigshospitalet, Denmark Not yet recruiting
Authors: Rahim MA, Zaman S, Amin MR, Uddin KN, Ma JC Abstract Histoplasmosis is uncommon in many parts of the world, including Bangladesh, where, in recent years, cases are increasingly reported. We sought to describe the sociodemographic characteristics, clinical presentation, investigations, treatment, and outcome of histoplasmosis in Bangladesh. We conducted a retrospective data review of published literature from 1962 to 2017, containing information on histoplasmosis in and/or from Bangladesh. Unpublished, well-documented histoplasmosis cases were also included. A total of 26 male patients aged 8-75 years, with...
More News: Anesthesia | Anesthesiology | Autoimmune Disease | Cardiogenic Shock | Cardiology | Complementary Medicine | Coumadin | Diets | Emergency Medicine | Heart | Hepatitis | Hepatitis B | Herbs | Jaundice | Liver | Liver Disease | Liver Transplant | Nutrition | Toxicology | Transplants | Urology & Nephrology | Warfarin