Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits

Translational Psychiatry, Published online: 23 January 2020; doi:10.1038/s41398-020-0685-1Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits
Source: Translational Psychiatry - Category: Psychiatry Authors: Source Type: research

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  The rent is due tomorrow; but then you’ll be left with only $10 for the week’s groceries. What do you do? Many people panic over money (or the lack of it), but for those of us with mental illness, it can feel like a life or death situation: It can trigger an even greater anxiety attack and/or depression. Or it may mean not being able to afford the medication that keeps you well enough to work. What can be done? In this Not Crazy episode, Gabe and Jackie discuss how you can gain a sense of control in these situations, and Jackie shares her own big money scare. (Transcript Available Below) SUBSCRIBE &a...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General LifeHelper Mental Health and Wellness Money and Financial Not Crazy Podcast Stress Source Type: blogs
z-Ruiz Martorell-Poveda Sleep disorders are often not regarded as an important health problem, despite their impact on heath. Insomnia is the most frequent sleep disorder in mental health. The aim is to quantify the prevalence of insomnia in a population with schizophrenic disorder and assess its influence on quality of life. This is a descriptive, analytical and cross-sectional study conducted in a sample of 267 schizophrenic patients over 18 years of age using consecutive non-probabilistic sampling. The variables of interest were collected by means of the "Cuestionario Oviedo de Sueño," "...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Communication Conferences General Mental Health America Mental Health and Wellness Policy and Advocacy Publishers connection Mental Health Advocacy Mental Health Policy Source Type: blogs
Our weekly round-up of the best psychology coverage from elsewhere on the web A study on bearded dragons has honed in on the brain structure responsible for generating slow wave sleep patterns, writes Elizabeth Pennisi at Science. An area of the brain called the claustrum — not previously known to even exist in reptiles — was key: when the structure was damaged, the lizards could still sleep but showed no slow wave patterns. It’s been an interesting few months for bearded dragon research: as we wrote in December, the lizards apparently also succumb to optical illusions. A mismatch between a student&rsqu...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Weekly links Source Type: blogs
This article summarizes the milestones in the development of lumateperone leading to this first approval for the treatment of schizophrenia.
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
Does the new coronavirus from China make you a little anxious? How concerned should we be? Is it a real threat or mostly hype? In today’s podcast, Dr. John Grohol, founder and editor-in-chief of PsychCentral.com, explains what the coronavirus is, how it compares to the flu and why it seems to have hit the panic button in a lot of people. He offers tips to avoid getting sick in general, and importantly, gives advice on how to keep our anxiety levels in check when it comes to new disease outbreaks, especially in how we seek information from the media. If you’d like to learn more about the coronavirus and how to...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic Disorders General Health-related Interview Podcast The Psych Central Show Source Type: blogs
When horses pull a carriage, sometimes they are wearing blinders over their eyes so they cannot look to the right or left. They can only look forward without any distractions coming into their view. This is a good picture of how I approach my life in recovery from schizophrenia. Metaphorically speaking, putting on blinders each day is a way I have learned to cope with my diagnosis of schizophrenia.  Every month I go to a veteran’s hospital to get blood work for my medication and to get my monthly injectable. On the drive there, I am the only one in the car so if I hear a voice, I block it out because the doors a...
Source: Psych Central - Category: Psychiatry Authors: Tags: Personal Stories Schizoaffective Disorder Schizophrenia breakthrough symptoms Delusions Hallucinations Paranoia Source Type: news
Abstract Trace amines, including β-phenylethylamine, p-octopamine, p-tyramine, and tryptamine, are produced in high levels in invertebrates where they play major roles in homeostasis regulation in a manner similar to that of adrenergic systems in mammals (Rutigliano et al. in Front Pharmacol 8:987, 2017; Gainetdinov et al. in Pharmacol Rev 70(3):549-620, 2018; Nagaya et al. in Neurosci Lett 329(3):324-328, 2002). In mammals, however, their levels are very low, initially prompting these molecules to be termed "trace" or "minor" amines in mammals with only a secondary role in the regulation ...
Source: Cellular and Molecular Neurobiology - Category: Cytology Authors: Tags: Cell Mol Neurobiol Source Type: research
Comorbidity is the presence of one or more additional conditions co-occurring with a primary condition. In this episode, host schizophrenic Rachel Star Withers with her cohost Gabe Howard will be discussing comorbidity with schizophrenia. Comorbidity is associated with worse health outcomes, more complex clinical management and increased health care costs. Occupational therapist and host of the podcast Occupied, Brock Cook, will be joining us to discuss ways that he works with people with schizophrenia to manage multiple health issues.  Highlights from “Comorbidity with Schizophrenia” Episode [01:28] What ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Antipsychotic Inside Schizophrenia Mental Health and Wellness Psychiatry Psychology Psychotherapy Bipolar disorder and schizophrenia comorbid comorbid psychiatric conditions Comorbidities Comorbidity Diagnosis Of Schizophrenia Livi Source Type: blogs
The article Self-Reported Sleep and Exercise Patterns in Patients with Schizophrenia: a Cross-Sectional Comparative Study written by Nancy Kiwan, Ziyad Mahfoud, Suhaila Ghuloum, Rifka Chamali, Arij Yehya, Samer Hammoudeh, Yahya Hani, Iman Amro, and Hassen Al-Amin
Source: International Journal of Behavioral Medicine - Category: Psychiatry Source Type: research
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