Vaccination of Infants with Meningococcal Group B Vaccine (4CMenB) in England

New England Journal of Medicine,Volume 382, Issue 4, Page 309-317, January 2020.
Source: New England Journal of Medicine - Category: Internal Medicine Authors: Source Type: research

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This study examines the attitudes and practices of HCPs working in college student health centers (SHCs) regarding the recommendation and administration of MenB to students. METHODS: The study was conducted as an online and phone survey of SHC HCPs from a sample of colleges across the United States between May 2017 and July 2018. Items compared college SHC policies and practices for MenB to those for MenACWY. It also assessed perceived barriers to and facilitators of MenB delivery to students. RESULTS: Among the 147 respondents, almost 50% more reported their SHC stocked and administered MenACWY (54.1%) than MenB...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
by Michael B. Arndt, Jason L. Cantera, Laina D. Mercer, Michael Kalnoky, Heather N. White, Gregory Bizilj, David S. Boyle, Eugenio L. de Hostos, Robert K. M. Choy Environmental enteric dysfunction (EED) is an intestinal disorder common among children in low-resource settings and is associated with increased risk of growth stunting, cognitive deficits, and reduced oral vaccine immunogenicity. The Micronutrient and EED Assessment Tool (MEEDAT) is a multiplexe d immunoassay that measures biomarkers previously associated with child growth faltering and/or oral vaccine immunogenicity: intestinal fatty acid–binding protei...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
[The Conversation Africa] In 2005, before most low- and middle-income countries started vaccinating children routinely for pneumococcal disease, it caused approximately 1.5 million deaths worldwide annually. About 700,000 to 1 million of these deaths were in children under five years. Pneumococcal disease occurs when Streptococcus pneumoniae invades a normally sterile area of the body, causing meningitis, pneumonia, septicaemia or other disease syndromes. Case fatality rates are very high for septicaemia (>20%) and meningitis (&
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
CONCLUSIONS: IPD required PICU admission in cases of septic shock and meningitis, and less so with complicated pneumonia. The percentage of admissions is greater in children with an underlying disease. Admission into the PICU involves a longer stay, complications during the acute phase, as well as sequelae, particularly neurological ones. The serotypes of the patients that were admitted to PICU were predominantly vaccine serotypes. PMID: 32998844 [PubMed - as supplied by publisher]
Source: Anales de Pediatria - Category: Pediatrics Authors: Tags: An Pediatr (Barc) Source Type: research
FRIDAY, Sept. 25, 2020 -- Routine vaccination with a quadrivalent meningococcal conjugate vaccine (MenACWY) is recommended for adolescents aged 11 to 12 years with a booster at age 16 years, according to a report published in the Sept. 24 issue of...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
ose Varicella vaccine is a live attenuated varicella-zoster virus (VZV). Like its parental strain called VZV pOka, the vaccine virus vOka retains some neurotropic properties. To better understand vOka neuropathogenesis, we reassessed 12 published cases of vOka meningitis that occurred in once-immunized and twice-immunized children, all of whom had bouts of herpes zoster preceding the central nervous system infection. Eight of the 12 meningitis cases occurred in children who had received only one immunization. There was no pattern to the time interval between varicella vaccination and the onset of herpes zoster with men...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Source: Human Vaccines and Immunotherapeutics - Category: Allergy & Immunology Authors: Source Type: research
Bacillus Calmette-Gu érin (BCG) vaccination, which has a protective effect against meningeal and miliary tuberculosis, has been widely used worldwide (Rodrigues et al., 1993; von Reyn, 2017). In Japan, the universal BCG vaccination policy has been applied since 1951 (Aoki, 1993). Adverse events such as subcutaneous abs cess and axillary lymphadenitis have been commonly reported (Aishwarya et al., 2015; Deeks et al., 2005). However, serious systemic adverse events including osteomyelitis or disseminated BCG, are exceedingly unusual and occur mostly in patients with immunodeficiency (Deeks et al., 2005; Suleiman et al., 2017).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Case Report Source Type: research
Background: Invasive meningococcal disease is a major cause of meningitis in children. An investigational meningococcal (serogroups A, C, Y, and W) tetanus toxoid conjugate vaccine (MenACYW-TT) could offer protection against invasive meningococcal disease in this population. This phase III study assessed the immunogenicity and safety of MenACYW-TT in children compared with a licensed quadrivalent meningococcal vaccine conjugated with diphtheria protein CRM197 (MenACWY-CRM). Methods: Healthy children 2–9 years of age in the United States, including Puerto Rico, were randomized (1:1) to receive MenACYW-TT (n = 499...
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Syndicated Local Vaccines Source Type: news
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