Dopamine treatment and cognitive functioning in individuals with Parkinson's disease. The "cognitive flexibility" hypothesis seems to work.

CONCLUSIONS: these findings document that high-flexibility processes are sensitive to dopamine neuromodulation in the early phases of PD. This is in line with the hypothesis that striatal dopamine pathways, affected early by PD, are precociously implicated in the expression of cognitive disorders in these individuals.
PMID: 24036966 [PubMed - as supplied by publisher]

Source: Behavioural Neurology - September 9, 2013 Category: Neurology Authors: Costa A, Peppe A, Mazzu I, Longarzo MC, Caltagirone C, Carlesimo GA Tags: Behav Neurol Source Type: research