Regulation of osteogenesis via miR-101-3p in mesenchymal stem cells by human gingival fibroblasts

ConclusionsHumoral factors from HGF suppressed osteogenesis in MSCs. The effect was regulated by miRNAs and undifferentiated MSC markers. miR-101-3p and ETV1 were the key factors and were regulated by IGF-1.

http://link.springer.com/10.1007/s00774-019-01080-2

Source: Journal of Bone and Mineral Metabolism - January 22, 2020 Category: Orthopaedics Source Type: research