The first flu vaccine in pill form may be around the corner, study finds

A new study showed that, when participants were given a new oral flu vaccine pill compared to the standard injectable, 29% of the tablet group fell ill compared to 35% of the shot group.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 19 February 2020Source: The LancetAuthor(s): Sarah Fidler, Wolfgang Stöhr, Matt Pace, Lucy Dorrell, Andrew Lever, Sarah Pett, Sabine Kinloch-de Loes, Julie Fox, Amanda Clarke, Mark Nelson, John Thornhill, Maryam Khan, Axel Fun, Mikaila Bandara, Damian Kelly, Jakub Kopycinski, Tomáš Hanke, Hongbing Yang, Rachel Bennett, Margaret JohnsonSummaryBackgroundAntiretroviral therapy (ART) cannot cure HIV infection because of a persistent reservoir of latently infected cells. Approaches that force HIV transcription from these cells, making them susceptible to killing—termed...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 19 February 2020Source: Microbial PathogenesisAuthor(s): Ali Dalir Ghaffari, Abdolhossein Dalimi, Fatemeh Ghaffarifar, Majid PirestaniAbstractToxoplasmosis, caused by Toxoplasma gondii, is a common parasitic disease, affecting almost one-third of the world's population. Currently, there are no effective treatments for inhibiting the formation of chronic tissue cysts in infected hosts. Thus, the production of appropriate vaccines against this pathogen is an important goal to avoid toxoplasmosis. considering the role of rhoptry antigens like ROP16 in virulence and satisfactory immunogenicit...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 18 February 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Rayane Rafei, Malaik Hawli, Marwan Osman, Fouad Dabboussi, Monzer HamzeAbstractThis review aimed to provide an updated scenario of the Group A Streptococcus (GAS) epidemiology in the Middle Eastern and North African (MENA) region with a special spotlight on the most prevalent emm types and macrolide resistance profiles. While the burden of invasive GAS infections is elusive to assess in the MENA region, the GAS prevalence ranged from 2.5% to up 42.4% in pharyngitis patients and from 2.4% to up 35.4% in healthy ca...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
WEDNESDAY, Feb. 19, 2020 -- There's been a crucial move forward in efforts to develop vaccines and treatments against the new COVID-19 coronavirus, U.S. researchers say. As of Wednesday, cases of infection with the virus have topped 74,000 (the vast...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
A better understanding of neutralizing antibody responses in hand foot and mouth disease could have important implications for vaccine development.Emerging Infectious Diseases
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
COVID-19, the infection caused by the newly identified coronavirus, is currently a disease with no pharmaceutical weapons against it. There's no vaccine to prevent it, and no drugs can treat it.WebMD Health News
Source: Medscape Infectious Diseases Headlines - Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
(University of Texas at Austin) Researchers have made a critical breakthrough toward developing a vaccine for the 2019 novel coronavirus by creating the first 3D atomic scale map of the part of the virus that attaches to and infects human cells. Mapping this part, called the spike protein, is an essential step so researchers around the world can develop vaccines and antiviral drugs to combat the virus. The paper is publishing Wednesday, Feb. 19 in the journal Science.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
According to the World Health Organization reports, billions of people around the world are at risk for malaria disease and it is important to consider the preventive strategies for protecting the people that ...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
Publication date: Available online 17 February 2020Source: Journal of Molecular Graphics and ModellingAuthor(s): Julia Liang, Anita Mantelos, Zheng Quan Toh, Stephanie M. Tortorella, Katherine Ververis, Jitraporn Vongsvivut, Keith R. Bambery, Paul V. Licciardi, Andrew Hung, Tom C. KaragiannisAbstractStreptococcus pneumoniae infection can lead to pneumococcal disease, a major cause of mortality in children under the age of five years. In low- and middle-income country settings where pneumococcal disease burden is high, vaccine use is low and widespread antibiotic use has led to increased rates of multi-drug resistant pneumo...
Source: Journal of Molecular Graphics and Modelling - Category: Molecular Biology Source Type: research
AbstractA cell ’s function can be regulated through its mechanism, and there has been a growing body of literature on how immune cells’ metabolism shapes its overall immune response. Manipulation of the cells metabolic activity through a biocompatible material would present new venues to the field of medicine. These agents are known as immunomodulatory and immunostimulatory reagents. They can either stimulate the immune response in a disease case where the immune response is lacking the strength or they can determine the nature and strength of the immune response as an immunomodulator according to our ne eds to...
Source: Inflammation - Category: Allergy & Immunology Source Type: research
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