The Role of Cardiac Rehabilitation in Reducing Major Adverse Cardiac Events in Heart Transplant Patients

Cardiac rehabilitation (CR) is a recommended treatment strategy for multiple populations to elicit well-established improvements in functional capacity, quality of life, and long-term outcomes.1 –6 Risk reduction has been shown in both all-cause and cardiovascular mortality with CR participation following percutaneous coronary intervention (PCI), myocardial infarction (MI), coronary artery bypass graft (CABG) surgery, and ventricular assist device implantation.1,7–10 More recently, long -term major adverse cardiac events (MACE) have also been investigated in these populations as a method of identifying high-risk patients for early integration of preventive care.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research

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This study aimed to explore the cardiologist adherence with ACC/AHA guidelines on discharge medications for patients admitted with acute coronary syndrome (ACS), assess the predictors of cardiologist non-adherence and measure the impact of pharmacist intervention on improving guideline adherence.MethodsThe study included two consecutive phases: observation and intervention. It was carried out at Al-Najaf Center for Cardiac Surgery and Catheterization, Iraq, from August through December 2018. In the observation phase, medical records were reviewed retrospectively in order to assess the adherence to guideline. The interventi...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2020Source: Molecular Immunology, Volume 120Author(s): Jian Du, Wei Lv, Sitong Yang, Jia Liu, Juan Zhen, Jiyan LengAbstractMyocardial infarction (MI) or heart attack is a deadly event with high prevalence. In the present study, we investigated the effects of the polypeptide copolymer glatiramer acetate (GA) in H9c2 rat cardiomyocytes exposed to oxygen-glucose deprivation/reperfusion injury. Immediately following MI, an acute inflammatory response is triggered that causes activation of various proinflammatory cytokines, infiltration of immune cells, and neovascularization. This response is largely me...
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
HEART ATTACKS are often caused by coronary heart disease, and risk of developing this is increased by a high-fat diet, high cholesterol and being overweight or obese. Research in the past has found a link between eating certain foods and heart disease, but a new study has confirmed a popular breakfast food is not as bad as first though.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The 2016 review for the US Preventive Services Task Force on statins for prevention of cardiovascular disease in adults had errors in the analysis of statins vs placebo and cardiovascular mortality. For the JUPITER trial, we interpreted “MI, stroke or cardiovascular death” as reported in the main trial publication as “myocardial death, stroke death, or cardiovascular death,” when it meant “nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death.” Therefore, the analysis erroneously included nonfatal myo cardial infarction and stroke events (83/8901 vs 157/8901 in the ros...
Source: JAMA - Category: General Medicine Source Type: research
A risk-based prevention strategy is the most widely accepted approach to guide clinician-patient decision-making for prevention of coronary artery disease (CAD). According to this approach, the intensity of prevention efforts is matched to the estimated risk of the individual. American College of Cardiology/American Heart Association guidelines currently recommend pooled cohort equations for initial risk assessment, which integrate age, systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, smoking status, and treatment for hypertension and diabetes to provide race- and sex-specific estimates of ...
Source: JAMA - Category: General Medicine Source Type: research
AbstractWe read with great pleasure the interesting study evaluating “The relationship between atherogenic index of plasma (AIP) and no-reflow in patients with acute ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention” by Süleymanoğlu M et al. The most important problem in the study was that they miscalculated the ir patients' AIP values. As a result of this miscalculation, all patients seemed to be at high cardiac risk. When calculating AIP, the unit of both triglyceride (TG) and high-density lipoprotein (HDL) levels should be taken in mmol. In calculating ...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
HEART attack is a serious medical emergency that happens when one of the major arteries supplying the heart with oxygen becomes blocked. A latest study reveals the best diet one can follow in order to significantly reduce their risk of the deadly condition. What is it?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Type 2 diabetes (T2D) is a metabolic disorder of insulin resistance — a reduced sensitivity to the action of insulin — which leads to high blood sugar, or hyperglycemia. Approximately 12% of American adults have T2D, and more than one-third of Americans have prediabetes, a precursor to T2D. This is a major public health concern, as T2D dramatically increases risk for heart disease, including heart attacks, atrial fibrillation, and heart failure. The development and progression of T2D is affected by many factors. Some, such as a person’s race/ethnicity, age, and gender cannot be modified. Others, including...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diabetes Exercise and Fitness Healthy Eating Heart Health Source Type: blogs
AbstractThe Medina classification is the most widespread method to describe bifurcation lesions. However, little is known regarding its prognostic impact. Therefore, the aim of this study is to assess the prognostic significance of the Medina classification following percutaneous coronary intervention (PCI). From a prospective registry of 738 consecutive patients undergoing PCI for bifurcation lesions, 505 were treated with second-generation drug-eluting stents (DES). Of these, 407 (80.6%) presented with “true bifurcation” (TB) lesions (Medina class 1.0.1, 1.1.1, 0.1.1) and 98 (19.4%) in all other categories (&...
Source: Heart and Vessels - Category: Cardiology Source Type: research
AbstractBackgroundRecent study reported that microRNA-142 (miR-142) were up-regulated in the atherosclerotic plaques, which may be responsible for pathogenesis of atherosclerosis. However, whether it associates with presence of acute myocardial infarction (AMI), and its prognostic value is still unknown. We, therefore, investigated the association between miR-142 expression and presence of AMI, and its prognostic value in AMI patients.MethodsWe included 300 AMI patients and 100 subjects as the control group. MiR-142 content was detected by quantitative real-time polymerase chain reaction. MiR-142 level was identified in al...
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
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