Daron Ferris to receive Penn Nursing Renfield Foundation Award for Global Women's Health
(University of Pennsylvania School of Nursing) Daron G. Ferris, M.D., the Founder of CerviCusco, will receive the 2020 Penn Nursing Renfield Foundation Award for Global Women's Health for his dedication to cervical cancer prevention among the indigenous women in Cusco, Peru. Ferris created CerviCusco, a nonprofit organization that ensures all women, including those with limited economic resources, have access to high quality and affordable health education and care, including screening, diagnosis, and treatment of cervical cancer.
Authors: Omara T, Kiprop AK, Ramkat RC, Cherutoi J, Kagoya S, Moraa Nyangena D, Azeze Tebo T, Nteziyaremye P, Nyambura Karanja L, Jepchirchir A, Maiyo A, Jematia Kiptui B, Mbabazi I, Kiwanuka Nakiguli C, Nakabuye BV, Chepkemoi Koske M Abstract The burden of neoplastic diseases is a significant global health challenge accounting for thousands of deaths. In Uganda, about 32,617 cancer cases were reported in 2018, accompanied by 21,829 deaths. In a view to identify some potential anticancer plant candidates for possible drug development, the current study was designed to compile the inventory of plants with reported a...
Conclusion: We have identified three up-regulated (PLOD2, ANLN, and AURKA) and a down-regulated DEGs (AR) with poor prognosis in CC on the basis of integrated bioinformatical methods, which could be regarded as potential therapeutic targets for CC patients. PMID: 32258155 [PubMed - in process]
Authors: Yi Y, Fang Y, Wu K, Liu Y, Zhang W Abstract Cervical Cancer is one of the leading causes of cancer-associated mortality in women. The present study aimed to identify key genes and pathways involved in cervical cancer (CC) progression, via a comprehensive bioinformatics analysis. The GSE63514 dataset from the Gene Expression Omnibus database was analyzed for hub genes and cancer progression was divided into four phases (phases I-IV). Pathway enrichment, protein-protein interaction (PPI) and pathway crosstalk analyses were performed, to identify key genes and pathways using a criterion nodal degree ≥5. Ge...
Authors: Tang Y, Zhao Y, Ran J, Wang Y Abstract MicroRNA (miR)-21 is known to act as an oncogene in cervical cancer by promoting cell proliferation and migration; however, the underlying molecular mechanisms have remained to be fully elucidated. The present study revealed that the gene expression levels of miR-21 and epithelial-mesenchymal transition (EMT)-associated transcription factor Zinc finger E-box-binding homeobox 1 (ZEB1), in cervical cancer and lymphatic metastatic carcinoma tissues were significantly higher than those in normal tissues (P
Publication date: Available online 8 April 2020Source: Pathology - Research and PracticeAuthor(s): Yingying Yuan, Xiaoqing Shi, Bingjie Li, Mengle Peng, Tao Zhu, Guanting Lv, Lu Liu, Huifang Jin, Liuxia Li, Dongchun Qin
Publication date: Available online 7 April 2020Source: Journal of EthnopharmacologyAuthor(s): Yumeng Wang, Chong Lu, Haixia Huang, Sheng Yao, Congjian Xu, Yang Ye, Suiqi Gui, Guiling Li
Despite the common perception that the human papilloma virus (HPV) is a requirement for the development of cervical cancer (CC), a considerable number of CCs test HPV negative. Presently, many countries are shifting to HPV primary CC screening, and it is of importance to increase the knowledge about the group of CCs that test HPV negative. The aim of this study was to reinvestigate a proportion of cervical tumors with a primary negative or invalid test result. Reinvestigation with repeated genotyping (targeting L1) was followed by analysis with an alternative target method (targeting E6/E7) on existing or additional tumor ...