Commentary: Cardiac Sarcoma Remains a Formidable Challenge
Conclusions: Endovascular brachytherapy is a novel, safe and effective therapeutic modality for non-resectable primary cardiac sarcomas either for palliation of obstruction, or tumor mass reduction to allow complete resection. PMID: 31969917 [PubMed]
We aim to evaluate the survival outcomes of primary cardiac sarcoma in a US nationwide cancer database.
Authors: Siontis BL, Leja M, Chugh R Abstract Introduction: Primary cardiac tumors are exceedingly rare, with approximately 75% representing benign lesions. Sarcoma represents the most common primary cardiac malignancy, with a wide range of sarcoma histologies represented. Symptoms at diagnosis vary based on tumor location. Multidisciplinary treatment including chemotherapy, surgery, and occasionally radiation is often warranted. Despite aggressive treatment, the overall prognosis for primary cardiac sarcoma (PCS) remains poor with a median survival of approximately 1 year.Areas covered: A PubMed search for the key...
ConclusionTumor size of> 4.0 cm is an independent predictor of poor prognosis, and is associated with the surgical outcome in PCS patients. Surgery significantly improves the prognosis in PCS patients with tumor size> 4.0 cm. Our findings have the potential to assist clinicians to better evaluate the prognosis of PCS patients and develop optimal therapeutic strategies.
This study was designed to determine whether postoperative therapy was associated with improved overall survival after resection.
Rationale: Malignant peripheral nerve sheath tumor (MPNST) is a very rare sarcoma of the heart, and few cases have been reported. Herein, we retrospectively reviewed clinical manifestations, imaging features and management of our patient and other reported cases. Patient concerns: A 32-year-old woman was referred to the emergency department of our institution with expiratory dyspnea, edema of face for a month. Diagnosis: The patient was initially diagnosed with asthma at a local hospital based on a history of fatigue, cough and expiratory dyspnea, as well as negative electroencephalogram (ECG) and chest radiography...