Somatostatin receptor expression and mTOR pathway activation in glioneuronal tumours of childhood

ConclusionsExpression of SSTRs and activation of mTOR pathway in paediatric glioneuronal tumour suggest that somatostatin analogues and mTOR inhibitors may have potential therapeutic implications in a subset of inoperable childhood glioneuronal tumours causing medically refractory epilepsy and/or tumour growth. Further clinical studies are warranted to validate these findings.

Source: Seizure - January 22, 2020 Category: Neurology Source Type: research