Physiologically based pharmacokinetic–pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans

Acta Pharmacologica Sinica, Published online: 22 January 2020; doi:10.1038/s41401-019-0353-2Physiologically based pharmacokinetic–pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans

Source: Acta Pharmacologica Sinica - January 21, 2020 Category: Drugs & Pharmacology Authors: Wei-min Kong Bin-bin Sun Zhong-jian Wang Xiao-ke Zheng Kai-jing Zhao Yang Chen Jia-xin Zhang Pei-hua Liu Liang Zhu Ru-jun Xu Ping Li Li Liu Xiao-dong Liu Source Type: research