BRCA Mutation Association with Recurrence Score and Discordance in a Large Oncotype Database.

CONCLUSIONS: Patients with deleterious BRCA mutations demonstrated no difference in rates of discordance as compared to BRCA-negative patients. We further demonstrated that patients with BRCA-positive tumors display higher RS than patients with BRCA-negative tumors.
PMID: 31962330 [PubMed - as supplied by publisher]

Source: Oncology - January 20, 2020 Category: Cancer & Oncology Authors: Blanter J, Zimmerman B, Tharakan S, Ru M, Cascetta K, Tiersten A Tags: Oncology Source Type: research