Perinatal Outcomes Associated with Maternal Asthma and its Severity and Control during Pregnancy

ConclusionWe did not observe an increased risk of pregnancy losses or malformations among women with asthma. However, we found an association between asthma severity and SGA; and between exacerbations late in pregnancy and preterm delivery and NICU admission.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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Publication date: Available online 16 February 2020Source: Molecular and Cellular ProbesAuthor(s): Parisa Atefvahid, Mohammad Hossein Modarressi, Ashraf Aleyasin, Zahra Noormohammadi
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
BACKGROUND: Childhood abuse has a negative effect on mental health during pregnancy; however, the association between childhood abuse and suicide ideation has received relatively little attention. METHOD: Women at 28 weeks or more into their pregna...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Condition:   Persistent Asthma Interventions:   Combination Product: fluticasone/formoterol k-haler (medium strength);   Combination Product: Standard of care (ICs/LABA high strength) Sponsors:   Mundipharma Pharmaceuticals S.L.;   Alpha Bioresearch S.L.;   Dynamic Solutions Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Condition:   Severe Asthma Intervention:   Other: No intervention Sponsor:   AstraZeneca Recruiting
Source: - Category: Research Source Type: clinical trials
CONCLUSIONS: Outcome-specific criteria are an important part of a systematic review and will facilitate study evaluations by epidemiologists with experience in evaluating studies using systematic review methods who may not have extensive discipline-specific experience in the outcomes being reviewed. PMID: 31299560 [PubMed - as supplied by publisher]
Source: Environment International - Category: Environmental Health Authors: Tags: Environ Int Source Type: research
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Author Affiliations open 1Biodesign Center for Environmental Security, Arizona State University, Tempe, Arizona, USA 2Green Science Policy Institute, Berkeley, California, USA 3Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA 4Environmental Working Group, Washington, District of Columbia, USA 5Department of Civil, Environmental, and Geo-Engineering, University of Minnesota, Minneapolis, Minnesota, USA 6Medical University of South Carolina, Department of Public Health Sciences, Charleston, South Carolina, USA 7Health Research Communicati...
Source: EHP Research - Category: Environmental Health Authors: Tags: Brief Communication Source Type: research
Author Affiliations open 1Infectious Diseases Division, icddr,b (International Centre for Diarrhoeal Disease Research, Bangladesh), Dhaka, Bangladesh 2Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden 3Maternal and Child Health Division, icddr,b, Dhaka, Bangladesh 4Department of Clinical Trial and Clinical Epidemiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan PDF Version (995 KB) Abstract About This Article Supplemental Material Background: Early-life arsenic exposure has been associated with reduced cell-mediated immunity, but little is known about its effects o...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
AbstractThe Hokkaido Study on Environment and Children ’s Health is an ongoing study consisting of two birth cohorts of different population sizes: the Sapporo cohort and the Hokkaido cohort. Our primary study goals are (1) to examine the effects of low-level environmental chemical exposures on birth outcomes, including birth defects and growth retard ation; (2) to follow the development of allergies, infectious diseases, and neurobehavioral developmental disorders and perform a longitudinal observation of child development; (3) to identify high-risk groups based on genetic susceptibility to environmental chemicals; ...
Source: Environmental Health and Preventive Medicine - Category: Environmental Health Source Type: research
AbstractIntroductionH1 antihistamines are used for the treatment of nausea and vomiting during pregnancy as well as the symptomatic relief of asthma, urticaria, allergy, and the common cold. Although they are overall felt to be safe during pregnancy, recently several studies have challenged this assumption, as millions of women are exposed to them in the first trimester.MethodsFollowing the guidelines of PRISMA, a systematic review was performed to retrieve all published articles involving H1-antihistamine exposure during pregnancy. Electronic databases including PubMed and EMBASE were searched for possibly relevant articl...
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research
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