Systematic review and meta-analysis of rates of clozapine-associated myocarditis and cardiomyopathy.

CONCLUSION: Clarity of diagnostic criteria for myocarditis remains a challenge. Observation bias may, in part, influence higher reported rates in Australia. Monitoring for myocarditis is warranted in the first 4 weeks, and treatment of comorbid metabolic syndrome and diabetes may reduce the risk of cardiomyopathy. The risks of myocarditis and cardiomyopathy are low and should not present a barrier to people with treatment refractory schizophrenia being offered a monitored trial of clozapine. PMID: 31957459 [PubMed - as supplied by publisher]
Source: The Australian and New Zealand Journal of Psychiatry - Category: Psychiatry Authors: Tags: Aust N Z J Psychiatry Source Type: research

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CONCLUSIONS: The average patient is middle aged (often male) with a history of subacute back pain, sometimes presenting fever and/or neurological damage on diagnosis. Acute phase reactants are frequently raised. Diabetes mellitus, endocarditis and immunosuppressed patients may have the worst chance of a good outcome, therefore these patients should be more carefully managed (always try to obtain an imaging-guided biopsy, correct antibiotic treatment, and a functional and clinical follow-up). PMID: 32446680 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
TYPE 2 diabetes does not pose a threat if you keep blood sugar levels under control. Diet acts as the ultimate bulwark against high blood sugar levels and a natural green powder has been proven to lower blood sugar.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 24 May 2020Source: Canadian Journal of DiabetesAuthor(s): Jacob M. Zamora, Jason M. Kong
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Does the Trump-hyped drug hydroxychloroquine have the potential to treat diabetes?
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
All about “blood glucose management” for diabetes: how does it work, and how can you master it?
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
This study, for instance, attributes a patient’s waitlist/transplant outcome to the very last dialysis facility the patient was associated with.  In epidemiology speak, this means the causal inference authors are trying to draw between for-profit status and good transplant outcomes is subject to time-varying confounding. As an example, if one is seeking an association between testosterone levels and risk of a heart attack, using the last testosterone level available would be a poor way of doing this study because testosterone levels are known to vary over time. The same applies to dialysis facilities. Patie...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Medical Practice Physicians Eric Weinhandl JAMA medical research public health Public Policy public policy research Source Type: blogs
Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Kehinde S. Olaniyi, Oluwatobi A. Amusa
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 24 May 2020Source: PhytomedicineAuthor(s): Nani Wang, Pingcui Xu, Xuping Wang, Weixuan Yao, Binjie Wang, Yuanzhao Wu, Dan Shou
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 24 May 2020Source: European Journal of Integrative MedicineAuthor(s): Xiaotong Wang, Haixiong Lin, Kangju Li, Tao Huang, Xiumin Jiang, Shengwei Wu, Aixiang Xiao, Lin Yu, Yongjun Chen
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Authors: Styła R, Kowalski J Abstract OBJECTIVES: Measuring severity of psychopathological symptoms using self-assessment questionnaires is important for clinical and scientific research. However, there is no widely-available Polish tool which measures both overall functioning and severity of a broad spectrum of psychopathological symptoms. This paper describesthe designing of such a tool -the General Functioning Questionnaire (GFQ-58). METHODS: Three studies were conducted to verify the validity and reliability of the GFQ-58: (1)a study comparing 30 individuals diagnosed with schizophrenia and 30 with no psyc...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
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